Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride
Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride (CAS: 118357-26-9) is a chemical compound with the formula C20H28N4O3 · 2HCl and a molecular weight of 445.38 g/mol. It functions as a sensitive chromogenic substrate for enzymes, particularly dipeptidyl aminopeptidase II. This compound is essential in biochemical research for enzyme activity assays and the study of cellular processes, especially within cell biology and neuroscience research.

Enzyme Activity Assays
Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride serves as a specific chromogenic substrate. Its cleavage by enzymes like dipeptidyl aminopeptidase II releases a detectable chromophore, allowing for the quantification of enzyme activity in various biological samples.
Biochemical Research
This compound is widely used in biochemical and cell biology laboratories for investigating enzyme kinetics and cellular signaling pathways. It aids in understanding the role of specific proteases in biological processes.
Cell Signaling Studies
In the field of neuroscience and cell signaling, this substrate helps researchers elucidate the function of peptidases involved in neuronal communication and other cellular regulatory mechanisms.
| Molecular weight | 445.38 |
|---|---|
| Empirical formula | C20H28N4O3 · 2HCl |
| Storage temperature | −20°C |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride used for?
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This compound is primarily used as a chromogenic substrate for the detection and quantification of enzyme activity, particularly dipeptidyl aminopeptidase II, in biochemical and cell biology research.
What is the CAS number and formula for Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride?
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The CAS number is 118357-26-9 and the formula is C20H28N4O3 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
What are the safety considerations when handling this chemical?
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This compound is classified with GHS08 symbol and a Warning signal word, with hazard statement H351, indicating it may cause cancer. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area. Avoid inhalation and contact.
How is Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of chemicals. This product is typically shipped and exported according to international regulations for chemical transport, with storage at -20°C.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by phone. Our team will be happy to assist you with your specific requirements.
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