Lithium diphenylphosphide solution
Lithium diphenylphosphide solution (CAS: 65567-06-8), with the linear formula (C 6 H 5 ) 2 PLi and a molecular weight of 192.12, is a key organophosphorus reagent. Supplied as a 0.5 M solution in tetrahydrofuran (THF), it serves as a potent nucleophile and base. Its primary applications lie in organic synthesis for introducing the diphenylphosphino group and in catalysis.
- IUPAC
- Diphenyl lithium phosphide,Diphenylphosphine lithium salt,Diphenylphosphino)lithium,Lithiodiphenyl phosphide,Lithiodiphenylphosphine
- Synonyms
- Diphenyl lithium phosphideDiphenylphosphine lithium saltDiphenylphosphino)lithiumLithiodiphenyl phosphideLithiodiphenylphosphine
Nucleophilic Reagent in Organic Synthesis
Lithium diphenylphosphide acts as a strong nucleophile, facilitating the formation of carbon-phosphorus bonds. It is used for the alkylation and arylation of diphenylphosphine groups in complex molecule synthesis.
Ligand Synthesis for Catalysis
This compound is instrumental in preparing diphenylphosphine-containing ligands. These ligands are widely employed in homogeneous catalysis, particularly in cross-coupling reactions and hydroformylation processes.
Phosphorus Precursor
As a source of the diphenylphosphino moiety, it functions as a precursor for a variety of organophosphorus compounds, including phosphonium salts and phosphine oxides.
| Molecular weight | 192.12 |
|---|---|
| Linear formula | (C6H5)2PLi |
| Boiling point | 65-67 °C |
| Density | 0.925 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -20 °C / -4 °F |
| Transport (UN / ADR) | UN 2924 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-19-34-37-40-50/53 |
| Safety statements (S) | 16-26-36/37/39-45-61 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lithium diphenylphosphide solution used for?
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Lithium diphenylphosphide solution is primarily used as a nucleophilic reagent in organic synthesis for introducing the diphenylphosphino group and in the synthesis of ligands for catalysis.
What are the CAS number and formula for Lithium diphenylphosphide solution?
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The CAS number is 65567-06-8. The linear formula is (C 6 H 5 ) 2 PLi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lithium diphenylphosphide solution at a concentration of 0.5 M in THF. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Lithium diphenylphosphide solution be handled safely?
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Lithium diphenylphosphide solution is highly reactive and flammable (flash point -20 °C). It is corrosive and can cause severe skin burns and eye damage. It is also harmful if inhaled and suspected of causing cancer. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. It may form explosive peroxides and should be stored away from heat and ignition sources.
How is Lithium diphenylphosphide solution packed and shipped?
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This product is UN 2924, Hazard Class 3, Packing Group II. It is carefully packed and shipped in accordance with international regulations for hazardous materials to ensure safe transport globally.
How can I request a sample or quote?
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To request a sample or a quotation for Lithium diphenylphosphide solution, please contact our sales team through the website or by phone, providing your specific requirements.
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