L-Leucine
L-Leucine (CAS 61-90-5) is an essential alpha-amino acid with the linear formula (CH3)2CHCH2CH(NH2)CO2H and a molecular weight of 131.17. It is crucial for protein synthesis and metabolic functions. This compound serves as a fundamental building block in peptide synthesis and biochemical research, finding applications in various scientific and industrial sectors requiring high-purity amino acid derivatives.
- IUPAC
- (S)-2-Amino-4-methylpentanoic acid
- Synonyms
- Leucine

Peptide Synthesis
L-Leucine is a key component in the synthesis of peptides and proteins, essential for creating custom peptides for research and therapeutic development. Its specific structure contributes to the overall properties of the resulting peptide chains.
Biochemical Research
Utilised as a standard in biochemical studies, L-Leucine is integral to research in cellular metabolism, protein structure-function relationships, and enzyme activity analysis. Its role as an essential amino acid makes it a frequent subject in metabolic pathway investigations.
Chemical Synthesis
This amino acid derivative serves as a chiral building block in organic synthesis. It is employed in the creation of complex molecules and pharmaceutical intermediates where stereospecificity is critical.
| Molecular weight | 131.17 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(NH2)CO2H |
| Assay | ≥98% (HPLC) |
| Grade | Vetec™ reagent grade |
| Impurities tested | isoleucine and methionine, essentially free |
| Melting point | >300 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Leucine used for?
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L-Leucine is used in peptide synthesis, biochemical research, and as a chiral building block in chemical synthesis. It is an essential amino acid crucial for protein synthesis and metabolic functions.
What are the CAS number and formula for L-Leucine?
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The CAS number for L-Leucine is 61-90-5, and its linear formula is (CH3)2CHCH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply for L-Leucine?
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Tech Serve Solutions supplies L-Leucine in Vetec™ reagent grade with an assay of ≥98% (HPLC). This product is not represented as USP, BP, or EP grade.
How should L-Leucine be handled and stored?
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L-Leucine has a GHS hazard classification requiring appropriate safety measures during handling. Refer to the Safety Data Sheet for detailed handling, storage, and disposal information. It is classified as WGK Germany 1.
Is L-Leucine a controlled substance?
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The provided data does not indicate that L-Leucine (CAS 61-90-5) is a controlled substance.
How is L-Leucine packed, shipped, and exported by TSS?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transit and compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a quote or sample of L-Leucine?
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To request a quote or sample for L-Leucine, please contact our sales team through the website or by phone, referencing the product CAS number 61-90-5.
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