L-Asparagine tert-butyl ester hydrochloride
L-Asparagine tert-butyl ester hydrochloride (CAS 63094-81-5) is a derivative of the amino acid asparagine. This compound, with a molecular weight of 224.69 g/mol, features a tert-butyl ester protecting group on the carboxyl function and a hydrochloride salt. It is primarily employed as a building block in peptide synthesis and in chemical biology research, facilitating the controlled incorporation of asparagine residues into peptides and proteins.
Peptide Synthesis
L-Asparagine tert-butyl ester hydrochloride serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis. The tert-butyl ester protects the C-terminus, allowing for controlled peptide chain elongation.
Chemical Biology
This compound is utilised in chemical biology to study protein structure and function. It can be incorporated into synthetic peptides to probe biological interactions or to develop novel biomolecules.
Organic Synthesis
As a functionalised amino acid, it is a valuable intermediate in complex organic synthesis pathways, particularly for creating molecules with biological relevance.
| Molecular weight | 224.69 |
|---|---|
| Linear formula | NH2COCH2CH(NH2)COOC(CH3)3 · HCl |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]/D +11.5±1.0°, c = 1 in methanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Asparagine tert-butyl ester hydrochloride used for?
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L-Asparagine tert-butyl ester hydrochloride is primarily used as a protected building block in peptide synthesis and in various chemical biology applications.
What are the CAS number and linear formula for L-Asparagine tert-butyl ester hydrochloride?
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The CAS number is 63094-81-5 and the linear formula is NH₂COCH₂CH(NH₂)COOC(CH₃)₃ · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Asparagine tert-butyl ester hydrochloride with an assay of ≥98.0% (TLC). This is a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should L-Asparagine tert-butyl ester hydrochloride be handled?
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When handling L-Asparagine tert-butyl ester hydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, and use a type N95 (US) or type P1 (EN143) respirator filter if necessary. The compound is classified under WGK Germany 3, indicating a hazard to water.
Is L-Asparagine tert-butyl ester hydrochloride a controlled substance?
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The provided data does not indicate that L-Asparagine tert-butyl ester hydrochloride is a controlled substance.
How is L-Asparagine tert-butyl ester hydrochloride packed and shipped?
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Tech Serve Solutions packs and ships L-Asparagine tert-butyl ester hydrochloride in compliance with all relevant regulations for chemical export.
How can I request a quote or sample?
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To request a quote or a sample of L-Asparagine tert-butyl ester hydrochloride, please contact the Tech Serve Solutions sales department via our website or designated contact channels.
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