Isobutyrophenone
Isobutyrophenone (CAS: 611-70-1) is a ketone with the linear formula C<sub>6</sub>H<sub>5</sub>COCH(CH<sub>3</sub>)<sub>2</sub> and a molecular weight of 148.20 g/mol. This organic compound is primarily utilised as a building block in chemical synthesis. It functions as a laboratory reagent and an internal standard in analytical chemistry. Isobutyrophenone is supplied by Tech Serve Solutions with a minimum assay of 97%.
- IUPAC
- 2-Methyl-1-phenyl-1-propanone,Isobutyrylbenzene
- Synonyms
- Isobutyrylbenzene2-Methyl-1-phenyl-1-propanone
Internal Standard in Pharmaceutical Analysis
Isobutyrophenone has been employed as an internal standard in the quantitative determination of hydroxyzine hydrochloride and benzyl alcohol within injection solutions. This application aids in ensuring the accuracy and reliability of pharmaceutical quality control testing.
Precursor in Organic Synthesis
The compound serves as a valuable intermediate in the synthesis of other organic molecules. Specifically, it has been used in the preparation of alpha-hydroxyisobutyrophenone, demonstrating its utility in constructing more complex chemical structures.
Reagent in Chemical Research
As a ketone and organic building block, Isobutyrophenone finds application in general chemical research and development. Its structure allows for various chemical transformations, making it a versatile reagent for exploring new synthetic pathways.
| Molecular weight | 148.20 |
|---|---|
| Linear formula | C6H5COCH(CH3)2 |
| Assay | 97% |
| Boiling point | 217 °C(lit.) |
| Density | 0.988 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.517(lit.) |
| Vapour pressure | 1 mmHg (50 °C) |
| Application | Isobutyrophenone was used as an internal standard in the determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions1. It was also used in the preparation of alpha-hydroxyisobutyrophenone2. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isobutyrophenone used for?
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Isobutyrophenone is used as an internal standard in analytical chemistry, particularly for determining substances like hydroxyzine hydrochloride and benzyl alcohol in injections. It also serves as a precursor in organic synthesis, for example, in preparing alpha-hydroxyisobutyrophenone, and as a general building block in chemical research.
What are the CAS number and chemical formula for Isobutyrophenone?
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The CAS number for Isobutyrophenone is 611-70-1, and its linear chemical formula is C<sub>6</sub>H<sub>5</sub>COCH(CH<sub>3</sub>)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isobutyrophenone with a minimum assay of 97%. This is typically considered a technical or research grade, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the key safety considerations when handling Isobutyrophenone?
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Isobutyrophenone is classified as a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Ensure adequate ventilation and avoid inhalation of vapours.
Is Isobutyrophenone a controlled substance?
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The provided data does not indicate that Isobutyrophenone (CAS 611-70-1) is a controlled or scheduled substance. However, customers should always verify its regulatory status in their specific jurisdiction.
How is Isobutyrophenone packaged and shipped?
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Isobutyrophenone is shipped according to relevant transport regulations, such as NA 1993 for combustible liquids. Specific packaging details are available upon request, and TSS, as an exporter, adheres to international shipping standards.
How can I request a quote or sample of Isobutyrophenone?
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To request a quote or a sample of Isobutyrophenone, please contact the Tech Serve Solutions sales team through our website or via direct inquiry, providing your specific requirements.
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