Ionomycin from Streptomyces conglobatus

CAS 56092-81-0C41H72O9Biochemicals & Reagents

Ionomycin (CAS: 56092-81-0, C41H72O9) is a high-purity ionophore antibiotic produced by <i>Streptomyces conglobatus</i>. This premium-grade chemical is instrumental in biochemical research, particularly for studying cellular processes involving calcium flux, endoplasmic reticulum stress, and apoptosis. Its ability to modulate cell division and cytokine production also makes it valuable in immunology and cell signalling investigations.

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Ionomycin from Streptomyces conglobatus (C41H72O9) — chemical structure, CAS 56092-81-0; Life Science, fine chemical supplied by Tech Serve Solutions

AntibacterialAntibioticsAntibiotics A to ZAntibiotics G-MAntibiotics by ApplicationBiochemicals and ReagentsChemical Structure ClassCore BioreagentsMechanism of ActionMiscellaneous

01 /Applications

Calcium Flux and Apoptosis Studies

Ionomycin is employed to investigate the intricate mechanisms of calcium signalling and its impact on endoplasmic reticulum stress, mitochondrial dysfunction, and programmed cell death (apoptosis).

Cell Division and Cytokine Regulation

This compound is used to regulate the cell division of mature human B cells and to stimulate the intracellular production of key cytokines, such as interferon, perforin, IL-2, and IL-4, often in conjunction with PMA.

Ionophore Research

As an ionophore, Ionomycin facilitates the transport of ions across biological membranes, making it a critical tool for studying membrane permeability and cellular ion homeostasis.

02 /Properties

Molecular weight	709.00
Empirical formula	C41H72O9
Assay	≥98% (HPLC)
Storage temperature	−20°C
Application	Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. It has been shown to induce central demyelination , inhibit adrenal bovine TREK-1 channels , and to regulate cell division of mature human B cells . It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochodrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22
Safety statements (S)	36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

56092-81-0

MDL number

MFCD06798385

PubChem substance

24896159

Beilstein registry

3642126

05 /Additional specifications

Quality Level	PREMIUM

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Ionomycin used for?

Ionomycin is primarily used in research to study calcium flux, apoptosis, cell division regulation, and cytokine production. It acts as an ionophore, influencing cell membrane permeability.

What are the CAS number and formula for Ionomycin?

The CAS number for Ionomycin is 56092-81-0, and its empirical formula is C41H72O9.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Ionomycin at a PREMIUM quality level with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should I handle Ionomycin safely?

Ionomycin is classified as harmful if swallowed (H302). When handling, use a dust mask type N95 (US), wear eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.

Is Ionomycin a controlled substance?

The provided data does not indicate that Ionomycin is a controlled substance. Please consult local regulations for specific compliance information.

How is Ionomycin packed, shipped, and exported?

Ionomycin is typically stored at -20°C. TSS ensures secure and compliant packing, shipping, and export of chemicals globally, adhering to all relevant regulations for research-grade reagents.

How can I request a sample or quote for Ionomycin?

To request a sample or a quote for Ionomycin, please contact our sales team through the website or by calling our dedicated line. Please specify the quantity required.