Indomethacin
Indomethacin (CAS 53-86-1) is a chemical compound with the molecular formula C19H16ClNO4 and a molecular weight of 357.79 g/mol. It is known for its potent anti-inflammatory and analgesic properties. Indomethacin is primarily utilized in scientific research and as a key intermediate in the synthesis of various pharmaceutical agents. Its applications extend to studies involving cellular processes and the development of therapeutic compounds.
- IUPAC
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
- Synonyms
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
Research Chemical
Indomethacin serves as a valuable research chemical for investigating inflammatory pathways and cellular signaling. It is employed in various laboratory studies to understand biological mechanisms.
Pharmaceutical Intermediate
This compound is utilized as a key intermediate in the synthesis of more complex pharmaceutical compounds. Its specific chemical structure makes it a useful building block in drug development.
Bioactive Small Molecule Studies
Indomethacin is used in research focused on bioactive small molecules, aiding in the understanding of their interactions within biological systems. This contributes to the broader field of chemical biology.
| Molecular weight | 357.79 |
|---|---|
| Empirical formula | C19H16ClNO4 |
| Assay | ≥99.0% (TLC) |
| Solubility | ethanol: soluble50 mg/mL, clear, yellow-green |
| Melting point | 155-162 °C |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indomethacin used for?
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Indomethacin is used as a research chemical for investigating inflammatory pathways and cellular signaling, and as an intermediate in the synthesis of pharmaceutical compounds.
What is the CAS number and molecular formula for Indomethacin?
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The CAS number for Indomethacin is 53-86-1, and its molecular formula is C19H16ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indomethacin with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Indomethacin be handled safely?
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Indomethacin is classified as 'Danger' (GHS06) and is acutely toxic (H300). Appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respirators (e.g., N100 US / P3 EN143) must be used. Handle in accordance with all applicable safety data sheets and regulations.
How is Indomethacin packed and exported?
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Indomethacin is packed securely for transport and is available for export globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for Indomethacin?
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To request a sample or a quotation for Indomethacin, please contact our sales team through the website or by phone, providing your specific requirements.
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