Indole-6-carboxaldehyde
Indole-6-carboxaldehyde (CAS: 1196-70-9; Formula: C9H7NO; MW: 145.16) is a vital organic building block featuring an aldehyde group attached to the indole heterocycle. This compound serves as a key intermediate in the synthesis of various complex organic molecules. Its applications span the preparation of potential therapeutic agents, including analogs of botulinum neurotoxin serotype A protease inhibitors and stilbene-based antitumor compounds, alongside its use in specialized organic synthesis procedures.
- IUPAC
- 6-Formylindole
Synthesis of Neurotoxin Protease Inhibitor Analogs
Indole-6-carboxaldehyde is utilised as a reactant in the preparation of analogue compounds targeting botulinum neurotoxin serotype A protease. This research contributes to the development of novel therapeutic strategies.
Antitumor Agent Synthesis
This aldehyde is employed as a key intermediate in the synthesis of stilbene-based compounds investigated for their potential antitumor activities. Its structural features are crucial for building these complex molecules.
Organic Synthesis of Gem-Dihalides
Indole-6-carboxaldehyde serves as a reactant in acid-catalyzed reactions for the preparation of aromatic gem-dihalides from aldehydes and acid halides, offering a route to specific halogenated intermediates.
| Molecular weight | 145.16 |
|---|---|
| Empirical formula | C9H7NO |
| Assay | 97% |
| Application | • Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors1• Reactant in synthesis of stilbene-based antitumor agents2• Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid halides3 |
| Melting point | 127-131 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indole-6-carboxaldehyde used for?
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Indole-6-carboxaldehyde is used as a reactant in the preparation of analogs of botulinum neurotoxin serotype A protease inhibitors, in the synthesis of stilbene-based antitumor agents, and in the acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid halides.
What are the CAS number and formula for Indole-6-carboxaldehyde?
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The CAS number is 1196-70-9 and the molecular formula is C9H7NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indole-6-carboxaldehyde with a minimum assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Indole-6-carboxaldehyde be handled?
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Indole-6-carboxaldehyde is classified as a Warning with hazards H317 (May cause an allergic skin reaction) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment including dust mask type N95, eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid contact with skin and eyes.
How is Indole-6-carboxaldehyde shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping Indole-6-carboxaldehyde worldwide.
How can I request a sample or quote for Indole-6-carboxaldehyde?
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Please contact our sales team to request a sample or a quotation for Indole-6-carboxaldehyde.
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