Hydroxyectoine
Hydroxyectoine (CAS: 165542-15-4; C6H10N2O3) is a cyclic amino acid derivative known for its exceptional osmoprotective and stabilizing properties. This naturally occurring compound is a powerful compatible solute, safeguarding cellular structures and biomolecules from environmental stressors like dehydration, extreme temperatures, and UV radiation. It finds significant utility in cosmetic formulations and biotechnology applications requiring enhanced product stability and efficacy.
- IUPAC
- (4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid,THP(A)

Cosmetic Formulations
Hydroxyectoine is incorporated into skincare products to provide superior hydration and protection against environmental damage. Its ability to stabilize skin cells enhances anti-aging effects and reduces irritation.
Biostabilization of Biomolecules
This compound serves as an effective agent for preserving the integrity of sensitive biomolecules such as enzymes, proteins, and nucleic acids. It is vital in the formulation of diagnostic kits and reagents.
Ophthalmic Solutions
Used in eye drops and contact lens solutions, Hydroxyectoine helps to moisturise and protect ocular tissues from dryness and stress, offering relief and improved comfort.
Biotechnology Research
In research settings, Hydroxyectoine is employed to enhance the stability of biological samples and improve the efficiency of enzymatic reactions under challenging conditions.
| Molecular weight | 158.16 |
|---|---|
| Empirical formula | C6H10N2O3 |
| Assay | ≥95% (HPLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxyectoine used for?
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Hydroxyectoine is primarily used for its excellent biostabilizing and osmoprotective properties, finding applications in cosmetics, biotechnology, and ophthalmic solutions to protect biomolecules and cells from environmental stress.
What are the CAS number and formula for Hydroxyectoine?
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Hydroxyectoine has the CAS number 165542-15-4 and the empirical formula C6H10N2O3.
What grade and purity does Tech Serve Solutions supply for Hydroxyectoine?
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Tech Serve Solutions supplies Hydroxyectoine with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Hydroxyectoine be handled safely?
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Handle Hydroxyectoine with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid inhalation of dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling guidelines.
What are the primary hazards associated with Hydroxyectoine?
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Hydroxyectoine is classified with the GHS07 symbol and a 'Warning' signal word. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is Hydroxyectoine packed and shipped by TSS?
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Hydroxyectoine is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Hydroxyectoine?
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To request a sample or quote for Hydroxyectoine, please contact our sales team through the website or by phone, providing your specific requirements.
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