Hydrocortisone 21-acetate
Hydrocortisone 21-acetate (CAS: 50-03-3), with the molecular formula C23H32O6 and a molecular weight of 404.50 g/mol, is a synthetic corticosteroid derivative. It is recognised for its anti-inflammatory properties and is primarily utilised as an analytical standard in various scientific applications. This compound plays a role in biochemical research and quality control processes within the pharmaceutical and analytical chemistry sectors. Its precise formulation ensures reliability for demanding laboratory analyses.
- IUPAC
- 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate,17-α-Hydroxycorticosterone acetate,17-Hydroxycorticosterone 21-acetate,21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione,4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
- Synonyms
- 17-Hydroxycorticosterone 21-acetate4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione17-α-Hydroxycorticosterone acetate
Analytical Standard
Hydrocortisone 21-acetate serves as a crucial analytical standard for chromatographic methods like HPLC. It is used to identify and quantify related substances in pharmaceutical formulations and research samples.
Biochemical Research
This compound is employed in biochemical studies investigating corticosteroid activity and metabolism. Researchers utilise it to explore cellular pathways and receptor interactions.
Quality Control
As a reference material, Hydrocortisone 21-acetate is integral to the quality control processes in the pharmaceutical industry. It aids in ensuring the purity and efficacy of related active pharmaceutical ingredients.
| Molecular weight | 404.50 |
|---|---|
| Empirical formula | C23H32O6 |
| Assay | ≥98% (HPLC) |
| Grade | VETRANAL™, analytical standard |
| Optical activity | [α]20/D +165±2°, c = 1% in dioxane |
| Suitability | meets USP testing specifications |
| Melting point | 223 °C (dec.)(lit.) |
Hazard statements
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... SERPINA6(866) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydrocortisone 21-acetate used for?
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Hydrocortisone 21-acetate is used as an analytical standard in chromatography and biochemical research, playing a role in quality control processes.
What is the CAS number and molecular formula for Hydrocortisone 21-acetate?
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The CAS number for Hydrocortisone 21-acetate is 50-03-3, and its molecular formula is C23H32O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydrocortisone 21-acetate in VETRANAL™, analytical standard grade, with an assay of ≥98% (HPLC). This product meets USP testing specifications.
What are the safety and handling considerations for Hydrocortisone 21-acetate?
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Hydrocortisone 21-acetate is classified with GHS08 symbol and 'Warning' signal word. It carries the hazard statement H361 (Suspected of damaging fertility or the unborn child). Appropriate personal protective equipment, including P281 (Use personal protective equipment as required), should be employed. For detailed handling procedures, consult the Safety Data Sheet.
Is Hydrocortisone 21-acetate a controlled substance?
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Based on the provided data, Hydrocortisone 21-acetate is not explicitly listed as a controlled substance. However, regulations can vary by jurisdiction, and users should verify local compliance.
How is Hydrocortisone 21-acetate packed and shipped?
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Tech Serve Solutions professionally packs and exports fine chemicals globally. Specific packaging details depend on the quantity and destination, adhering to international shipping regulations.
How can I request a sample or quote for Hydrocortisone 21-acetate?
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To request a sample or quote for Hydrocortisone 21-acetate, please contact our sales team via the website or direct inquiry channels.
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