Hydrocortisone
Hydrocortisone (CAS: 50-23-7, C21H30O5, MW: 362.46) is a naturally occurring glucocorticoid. It is widely used in pharmaceutical research and as a building block in complex molecule synthesis. Its suitability for cell culture and validated assay make it a reliable choice for advanced research applications.
- IUPAC
- 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione,17-Hydroxycorticosterone,4-Pregnene-11β,17α,21-triol-3,20-dione,Cortisol,Kendall’s compound F,Reichstein’s substance M
- Synonyms
- 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione17-Hydroxycorticosterone4-Pregnene-11β,17α,21-triol-3,20-dioneCortisolKendall’s compound FReichstein’s substance M
Pharmaceutical Research
Hydrocortisone serves as a crucial intermediate and reference standard in pharmaceutical development and drug discovery processes. Its well-defined properties are essential for quality control and analytical validation.
Chemical Synthesis
Utilized as a chiral building block in asymmetric synthesis, Hydrocortisone is key to constructing complex molecular architectures. It enables the precise stereochemical control required for advanced organic chemistry.
Cell Culture Studies
With verified suitability for cell culture, this compound is employed in biological research to investigate cellular responses and mechanisms. Its inclusion in media supports various in vitro experimental models.
| Molecular weight | 362.46 |
|---|---|
| Empirical formula | C21H30O5 |
| Assay | 98% |
| Concentration | 50 μM |
| Optical activity | [α]25/D +166°, c = 1 in ethanol |
| Storage temperature | −20°C |
| Impurities tested | endotoxin, tested |
| Melting point | 211-214 °C(lit.) |
| Suitability | suitable for cell culture |
Hazard statements
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Sterility | γ-irradiated |
|---|---|
| Potency | 0.004-5 μg/mL |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydrocortisone used for?
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Hydrocortisone is used in pharmaceutical research, chemical synthesis as a chiral building block, and for cell culture studies.
What is the CAS number and formula for Hydrocortisone?
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The CAS number for Hydrocortisone is 50-23-7 and its empirical formula is C21H30O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydrocortisone with an assay of 98%. It is suitable for cell culture and is γ-irradiated and sterile, but not represented as USP, BP, or EP grade.
How should Hydrocortisone be handled?
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Handle Hydrocortisone with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, due to potential reproductive hazard (H361). Store at −20°C.
How is Hydrocortisone packed and exported?
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Hydrocortisone is packed and exported under stringent conditions to maintain its integrity, suitable for global research and industrial needs.
How can I request a sample or quote for Hydrocortisone?
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To request a sample or quote, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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