Hydrocinchonine
Hydrocinchonine (CAS 485-65-4), with the molecular formula C19H24N2O, is a cinchona alkaloid derivative. It is primarily utilised in chemical synthesis as a chiral ligand and organocatalyst. Its specific stereochemical properties make it valuable for asymmetric synthesis, enabling the enantioselective formation of complex organic molecules. Available from TSS with a purity of ≥95.0% (sum of enantiomers, HPLC), it is a key reagent for advanced chemical research and development.
- IUPAC
- Dihydrocinchonine
Asymmetric Synthesis
Hydrocinchonine serves as a crucial chiral catalyst or ligand in asymmetric synthesis. It facilitates enantioselective reactions, enabling the preferential formation of one stereoisomer over another, which is vital for producing enantiomerically pure compounds in pharmaceuticals and fine chemicals.
Chiral Ligand
As a Cinchona alkaloid derivative, hydrocinchonine functions as a privileged chiral ligand in various metal-catalyzed reactions. Its defined stereochemistry allows for precise control over the stereochemical outcome of catalytic transformations.
Chemical Synthesis
This compound is a versatile reagent in organic synthesis, particularly where stereocontrol is paramount. It finds application in the construction of complex molecular architectures requiring high enantiopurity.
| Molecular weight | 296.41 |
|---|---|
| Empirical formula | C19H24N2O |
| Assay | ≥95.0% (sum of enantiomers, HPLC)≥97.0% (NT) |
| Optical activity | [α]20/D +197±4°, c = 0.25% in ethanol |
| Melting point | 269-272 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydrocinchonine used for?
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Hydrocinchonine is used primarily as a chiral catalyst and ligand in asymmetric synthesis and general chemical synthesis. Its stereochemical properties are exploited to achieve enantioselective transformations.
What is the CAS number and formula for Hydrocinchonine?
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The CAS number for Hydrocinchonine is 485-65-4, and its molecular formula is C19H24N2O.
What grade and purity does Tech Serve Solutions supply for Hydrocinchonine?
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Tech Serve Solutions supplies Hydrocinchonine with an assay of ≥95.0% (sum of enantiomers, HPLC) and ≥97.0% (NT). We do not represent this product as USP, BP, or EP grade.
What are the safety hazards associated with Hydrocinchonine?
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Hydrocinchonine is classified with GHS07 symbol and 'Warning' signal word. It is harmful if swallowed (H302), harmful in contact with skin (H312), and harmful if inhaled (H332). Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used.
How is Hydrocinchonine packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Hydrocinchonine is carefully packed to ensure integrity during transit and is available for export worldwide.
How can I request a quote or sample of Hydrocinchonine?
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To request a quote or sample of Hydrocinchonine, please contact our sales team through the website or by phone, providing your specific requirements.
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