Hexamethyleneimine
Hexamethyleneimine (CAS: 111-49-9), with the molecular formula C6H13N and a molecular weight of 99.17 g/mol, is a saturated heterocyclic amine. It is a key intermediate in organic synthesis, often employed as a building block for more complex molecules in the pharmaceutical and chemical industries. Its specific structural features make it valuable for creating specialised heterocyclic compounds.
- IUPAC
- Hexahydro-1H-azepine,Homopiperidine
- Synonyms
- HomopiperidineHexahydro-1H-azepine
Pharmaceutical Intermediate
Hexamethyleneimine serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates. Its cyclic amine structure facilitates the introduction of specific functionalities into target molecules.
Organic Synthesis Building Block
As a versatile heterocyclic building block, this compound is utilised in the construction of diverse organic structures. It is particularly useful in reactions requiring a secondary amine moiety within a ring system.
Chemical Research and Development
In research laboratories, Hexamethyleneimine is used to explore novel chemical pathways and to synthesise new compounds with potential applications in materials science and agrochemicals.
| Molecular weight | 99.17 |
|---|---|
| Empirical formula | C6H13N |
| Assay | 99% |
| Boiling point | 138 °C/749 mmHg(lit.) |
| Density | 0.88 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.466(lit.) |
| Vapour pressure | 7.4 mmHg (21.1 °C) |
Hazard statements
- H225Highly flammable liquid and vapour
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 2493 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-20-25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexamethyleneimine used for?
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Hexamethyleneimine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates and other complex chemical compounds.
What are the CAS number and formula for Hexamethyleneimine?
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The CAS number for Hexamethyleneimine is 111-49-9, and its molecular formula is C6H13N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hexamethyleneimine with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Hexamethyleneimine be handled safely?
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Hexamethyleneimine is a flammable liquid and vapour, causes severe skin burns and eye damage, and is toxic if swallowed or inhaled. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, face shield, and a suitable respirator. Refer to the Safety Data Sheet for detailed guidance.
How is Hexamethyleneimine packed and exported?
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Hexamethyleneimine is packed according to UN 2493 Class 8(3) Packing Group II regulations for safe transportation and export. Specific packaging details are available upon request.
How can I request a quote or sample for Hexamethyleneimine?
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To request a quote or sample of Hexamethyleneimine, please contact our sales team through the TSS website or provide your requirements directly.
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