Hexamethylene diisocyanate
Hexamethylene diisocyanate (HDI), CAS 822-06-0, with the chemical formula OCN(CH2)6NCO and a molecular weight of 168.19 g/mol, is a key difunctional isocyanate monomer. It is widely utilised as a building block in the synthesis of advanced polymers, particularly polyurethanes. Its reactive isocyanate groups readily undergo addition reactions with compounds containing active hydrogen atoms, facilitating the creation of durable materials.
- IUPAC
- 1,6-Diisocyanatohexane
- Synonyms
- 1,6-Diisocyanatohexane

Polyurethane Coatings
HDI is a crucial component in the formulation of high-performance polyurethane coatings, offering excellent weather resistance, UV stability, and abrasion resistance for automotive, industrial, and architectural applications.
Adhesives and Sealants
It serves as a crosslinking agent in the production of polyurethane adhesives and sealants, providing strong bonding capabilities and flexibility for various assembly and sealing tasks.
Elastomers Production
HDI is employed in the synthesis of polyurethane elastomers, contributing to materials with superior mechanical properties, resilience, and chemical resistance suitable for demanding industrial components.
Fibre and Textile Treatments
This isocyanate monomer is used to impart specific properties to fibres and textiles, enhancing durability, water repellency, or other performance characteristics.
| Molecular weight | 168.19 |
|---|---|
| Linear formula | OCN(CH2)6NCO |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 82-85 °C/0.1 mmHg |
| Density | 1.047 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.453 |
| Vapour pressure | 0.05 mmHg (25 °C) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 135 °C / 275 °F |
| Transport (UN / ADR) | UN 2281 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23-36/37/38-42/43 |
| Safety statements (S) | 26-28-38-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexamethylene diisocyanate (HDI) used for?
+
Hexamethylene diisocyanate (HDI) is primarily used as a building block in the synthesis of polyurethane coatings, adhesives, sealants, and elastomers, imparting durability, flexibility, and resistance properties to the final materials.
What is the CAS number and chemical formula for Hexamethylene diisocyanate?
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The CAS number for Hexamethylene diisocyanate is 822-06-0, and its chemical formula is OCN(CH2)6NCO.
What grade and purity does Tech Serve Solutions supply for Hexamethylene diisocyanate?
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Tech Serve Solutions supplies Hexamethylene diisocyanate in 'purum' grade with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with Hexamethylene diisocyanate?
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Hexamethylene diisocyanate is a dangerous substance classified with GHS06 and GHS08 symbols. It causes skin irritation (H315), allergic skin reactions (H317), serious eye irritation (H319), is toxic if inhaled (H331), can cause allergy or asthma symptoms or breathing difficulties if inhaled (H334), and may cause respiratory irritation (H335). Strict adherence to safety protocols and appropriate personal protective equipment, including respiratory protection, is essential.
How is Hexamethylene diisocyanate typically packed and exported?
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Hexamethylene diisocyanate is packed and exported according to international shipping regulations for hazardous materials, identified under UN 2281, Class 6.1, Packing Group II.
How can I request a quote or sample of Hexamethylene diisocyanate?
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To request a quote or a sample of Hexamethylene diisocyanate, please contact our sales department through the website or by phone, providing your specific requirements.
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