Heptakis(2,6-di-O-methyl)-β-cyclodextrin
Heptakis(2,6-di-O-methyl)-β-cyclodextrin (CAS: 51166-71-3) is a methylated derivative of beta-cyclodextrin with a molecular weight of 1331.36 g/mol. This premium grade compound is widely utilised in physicochemical studies, including the formation of inclusion complexes and interactions with micelles. It serves as a cell penetration enhancer in cellular transport studies and is employed to improve the solubilisation and stability of various pharmaceutical agents.
- IUPAC
- 2,6-Di-O-methyl-β-cyclodextrin,Dimethyl β-cyclodextrin
- Synonyms
- C56H98O352,6-Di-O-methyl-β-cyclodextrinDimethyl β-cyclodextrin
Physicochemical Studies
Utilised in the investigation of inclusion complex formation and molecular interactions, particularly with micelles, where it can induce micellar rupture.
Pharmaceutical Applications
Enhances the physicochemical properties and biopharmaceutical profile of drugs, notably improving their solubility and stability. It also functions as a cell penetration enhancer in drug delivery research.
Analytical Chemistry
Serves as a reagent in analytical and chromatographic applications, including capillary electrophoresis, and as a chiral mobile phase additive.
Biochemical Research
Probes diffusion and single molecule interactions with reconstituted membrane proteins, and is studied for its interactions with cholesterol.
| Molecular weight | 1331.36 |
|---|---|
| Empirical formula | C56H98O35 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +158±3°, c = 10% in H2O |
| Impurities tested | ≤3% water |
| Application | Reactant involved in:• Physicochemical studies of inclusion complexes1• Probing diffusion and single molecule interactions with reconstituted membrane proteins2• Interactions with micelles causing micellar rupture3• Studying cellular transport, used as a cell penetration enhancer4• Physicochemical and biopharmaceutical improvement of drugs5 particularly with solubilization and stability6• Interactions with cholesterol7 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Heptakis(2,6-di-O-methyl)-β-cyclodextrin used for?
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It is used in physicochemical studies of inclusion complexes and molecular interactions, as a cell penetration enhancer, to improve drug solubility and stability, and in analytical applications like chromatography and capillary electrophoresis.
What is the CAS number and formula for Heptakis(2,6-di-O-methyl)-β-cyclodextrin?
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The CAS number is 51166-71-3, and the empirical formula (Hill notation) is C56H98O35.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a PREMIUM quality level with an assay of ≥98.0% (TLC) and ≤3% water content. It is not represented as USP/BP/EP grade.
What are the safety and handling recommendations for Heptakis(2,6-di-O-methyl)-β-cyclodextrin?
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Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany rating of 3.
How is Heptakis(2,6-di-O-methyl)-β-cyclodextrin packed, shipped, and exported?
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Tech Serve Solutions, a specialist global supplier and exporter since 1998, ensures appropriate packaging for safe transport and handles international export procedures.
How can I request a sample or quote for Heptakis(2,6-di-O-methyl)-β-cyclodextrin?
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Please contact our sales team directly to request a sample or obtain a quotation for this product.
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