Ethyl 5-hydroxy-2-methylindole-3-carboxylate
Ethyl 5-hydroxy-2-methylindole-3-carboxylate (CAS 7598-91-6), a C12H13NO3 molecule with a molecular weight of 219.24 g/mol, is a valuable heterocyclic building block. This indole derivative is primarily utilised as a reactant in the synthesis of diverse biologically active compounds. Its applications span the development of potential anti-inflammatory agents, analgesics, and novel therapeutics targeting obesity and specific receptor systems.
- IUPAC
- NSC 405600
Synthesis of Anti-inflammatory and Analgesic Agents
This compound serves as a key intermediate in the preparation of novel molecules investigated for their potential anti-inflammatory and analgesic properties. Research indicates its utility in developing compounds that may target pain and inflammation pathways.
Development of Histamine-3 Receptor Inverse Agonists
It is employed as a reactant in the synthesis of histamine-3 receptor inverse agonists. These compounds are being explored for their therapeutic potential in the treatment of obesity and related metabolic disorders.
Inhibitors of Tubulin Polymerization
Ethyl 5-hydroxy-2-methylindole-3-carboxylate is utilized in the synthesis of compounds designed to inhibit tubulin polymerization. These molecules are of interest for their potential anti-cancer applications.
Prodrug Synthesis
The compound acts as a precursor in the development of specific prodrugs, such as 4,7-dioxoindole-3-methyl prodrugs, which are designed for improved therapeutic delivery and efficacy.
Muscarinic Receptor Antagonists
It is used as a building block in the synthesis of antagonists for M4 muscarinic receptors. These molecules are investigated for their potential in treating neurological and psychiatric conditions.
| Molecular weight | 219.24 |
|---|---|
| Empirical formula | C12H13NO3 |
| Assay | 97% |
| Application | Reactant for preparation of:• Potential anti-inflammatory and analgesic agents1• Histamine-3 receptor inverse agonists for the treatment of obesity2• Tubulin Polymerization Inhibitors3• 4,7-dioxoindole-3-methyl prodrugs4• Antagonists at M4 muscarinic receptors5 |
| Melting point | 205-208 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 5-hydroxy-2-methylindole-3-carboxylate used for?
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Ethyl 5-hydroxy-2-methylindole-3-carboxylate is used as a reactant in the synthesis of potential anti-inflammatory and analgesic agents, histamine-3 receptor inverse agonists for obesity treatment, tubulin polymerization inhibitors, 4,7-dioxoindole-3-methyl prodrugs, and antagonists at M4 muscarinic receptors.
What is the CAS number and formula for Ethyl 5-hydroxy-2-methylindole-3-carboxylate?
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The CAS number is 7598-91-6 and the empirical formula (Hill notation) is C12H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 5-hydroxy-2-methylindole-3-carboxylate with an assay of 97%. This is a research grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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Handling requires personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK 2 (Germany), indicating it is hazardous to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging for safe transport. Please contact us for specific details regarding shipping and export of Ethyl 5-hydroxy-2-methylindole-3-carboxylate.
How can I request a sample or quote for Ethyl 5-hydroxy-2-methylindole-3-carboxylate?
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To request a sample or a quote, please contact the TSS sales department through our website or by phone. Our team will assist you promptly.
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