Ethyl 5-fluoroindole-2-carboxylate
Ethyl 5-fluoroindole-2-carboxylate (CAS: 348-36-7), with the molecular formula C11H10FNO2 and a molecular weight of 207.20 g/mol, is a fluorinated heterocyclic building block. This compound serves as a key reactant in the synthesis of various biologically active molecules. Its applications are primarily within pharmaceutical research and development, contributing to the creation of potential therapeutic agents for diverse medical conditions.
Antitumor Agent Synthesis
This compound is utilised as a reactant in the preparation of potential antitumor agents. Its indole core and fluorine substituent can be incorporated into novel drug candidates.
Antihyperlipidemic Agent Development
Ethyl 5-fluoroindole-2-carboxylate functions as a reactant in the synthesis pathways for antihyperlipidemic agents. These compounds aim to manage elevated lipid levels.
Factor Xa Inhibitor Preparation
The chemical serves as a building block in the development of factor Xa inhibitors. These are investigated for their anticoagulant properties.
Antiarrhythmic Agent Research
It is employed as a reactant for the preparation of agents with potential antiarrhythmic activity, targeting irregularities in heart rhythm.
Cytosolic Phospholipase A2 Inhibitor Synthesis
This compound is a reactant for the preparation of inhibitors of cytosolic phospholipase A2, a target in inflammatory disease research.
Thromboxane Receptor Antagonist Synthesis
It is used as a reactant in the Mitsunobu reaction for the preparation of thromboxane receptor antagonists and thromboxane synthase inhibitors.
| Molecular weight | 207.20 |
|---|---|
| Empirical formula | C11H10FNO2 |
| Assay | 96% |
| Application | • Reactant for preparation of antitumor agents1• Reactant for preparation of antihyperlipidemic agents2• Reactant for preparation of factor Xa inhibitors3• Reactant for preparation of potential antiarrhythmic agents4• Reactant for preparation of inhibitors of the cytosolic phospholipase A25• Reactant for preparation of thromboxane receptor antagonist and thromboxane synthase inhibitor via Mitsunobu reaction6 |
| Melting point | 146-150 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 5-fluoroindole-2-carboxylate used for?
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Ethyl 5-fluoroindole-2-carboxylate is primarily used as a reactant and building block in the synthesis of potential therapeutic agents, including antitumor agents, antihyperlipidemic agents, factor Xa inhibitors, antiarrhythmic agents, and others.
What are the CAS number and formula for Ethyl 5-fluoroindole-2-carboxylate?
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The CAS number for Ethyl 5-fluoroindole-2-carboxylate is 348-36-7, and its empirical formula is C11H10FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 5-fluoroindole-2-carboxylate with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
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When handling Ethyl 5-fluoroindole-2-carboxylate, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 3, indicating a high hazard level in water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports fine chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a sample or quote for Ethyl 5-fluoroindole-2-carboxylate?
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To request a sample or quote for Ethyl 5-fluoroindole-2-carboxylate, please contact our sales department via the website or by phone.
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