Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin (CAS 55216-11-0) is a methylated cyclodextrin derivative with a molecular weight of 1429.54 g/mol. This compound serves as a crucial chiral additive in liquid chromatography for enantiomer resolution and is also employed in capillary electrophoresis for the chiral separation of basic drug substances. Its specific structure allows for effective molecular complexation, making it valuable in analytical chemistry.
- IUPAC
- 2,3,6-Tri-O-methyl-β-cyclodextrin,Trimethyl-β-cyclodextrin
- Synonyms
- 55216-11-0C63H112O352,3,6-Tri-O-methyl-β-cyclodextrinTrimethyl-β-cyclodextrin
Chiral Chromatography Additive
Used as a chiral additive in liquid chromatography to achieve the resolution of enantiomers. Its complexation properties enable the separation of stereoisomers in analytical and preparative applications.
Capillary Electrophoresis (CE) for Enantioseparation
Applied in capillary electrophoresis techniques for the chiral separation of basic drug substances. It functions as a mobile phase additive to differentiate between enantiomers.
Analytical Reagent
A versatile analytical reagent employed in various chromatographic and electrophoretic methods. Its role in chiral recognition is key to its utility in quality control and research.
| Molecular weight | 1429.54 |
|---|---|
| Empirical formula | C63H112O35 |
| Assay | ≥98.0% (TLC)≥98.0% |
| Solubility | H2O: soluble50 mg/mL, slightly turbid, colorless |
| Optical activity | [α]25/D +157±4°, c = 1% in H2O |
| Storage temperature | 2-8°C |
| Application | Chiral additive in liquid chromatography for enantiomer resolution.1 Chiral separation of basic drug substances by capillary electrophoresis.2 |
| Melting point | 170-178 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin used for?
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It is primarily used as a chiral additive in liquid chromatography for enantiomer resolution and in capillary electrophoresis for the chiral separation of basic drug substances.
What are the CAS number and formula for this compound?
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The CAS number is 55216-11-0, and the empirical formula (Hill notation) is C63H112O35.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin with an assay of ≥98.0% (TLC) and ≥98.0%. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
How should Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C. Refer to the safety data sheet for detailed hazard information. The WGK Germany is 3.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant and secure packaging and shipment worldwide.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or sample of Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin.
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