Glyoxylic acid monohydrate
Glyoxylic acid monohydrate (CAS: 563-96-2) is a chemical compound with the linear formula HCOCO2H·H2O and a molecular weight of 92.05 g/mol. This white crystalline solid is a versatile building block in organic synthesis. It serves as a key intermediate in the production of various fine chemicals, pharmaceuticals, and agrochemicals, owing to its reactive aldehyde and carboxylic acid functionalities.
- IUPAC
- Formylformic acid,Oxoethanoic acid
- Synonyms
- Formylformic acidOxoethanoic acid

Pharmaceutical Intermediate
Glyoxylic acid monohydrate is employed as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and advanced pharmaceutical intermediates. Its structure allows for diverse chemical transformations crucial for drug development.
Agrochemical Synthesis
This compound is utilised in the manufacture of certain pesticides and herbicides. The aldehyde and carboxylic acid groups facilitate reactions leading to complex agrochemical molecules.
Fine Chemical Production
As a valuable C2 building block, glyoxylic acid monohydrate finds application in the synthesis of various fine chemicals, including flavour and fragrance compounds, dyes, and specialty polymers.
Organic Synthesis Reagent
It acts as a versatile reagent in academic and industrial research laboratories for introducing the glyoxylyl moiety into organic molecules, enabling the construction of complex chemical structures.
| Molecular weight | 92.05 |
|---|---|
| Linear formula | HCOCO2H · H2O |
| Assay | ≥97.0% (T) |
| Grade | purum |
| Boiling point | 100 °C(lit.) |
| Solubility | H2O: soluble0.1 g/mL, clear |
| Storage temperature | 2-8°C |
| Melting point | 49-52 °C(lit.)~57 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glyoxylic acid monohydrate used for?
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Glyoxylic acid monohydrate is primarily used as a building block and intermediate in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals, as well as a reagent in organic synthesis.
What is the CAS number and formula for Glyoxylic acid monohydrate?
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The CAS number is 563-96-2, and the linear formula is HCOCO2H·H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Glyoxylic acid monohydrate with a purity of ≥97.0% (T) and a grade of purum. We do not represent this product as USP, BP, or EP grade.
How should Glyoxylic acid monohydrate be handled and stored?
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Glyoxylic acid monohydrate is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Store in a cool, well-ventilated area, preferably under refrigeration at 2-8°C.
Is Glyoxylic acid monohydrate a controlled substance?
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The provided data does not indicate that Glyoxylic acid monohydrate is a controlled substance.
How is Glyoxylic acid monohydrate packed and shipped?
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Glyoxylic acid monohydrate is typically packed in accordance with international transport regulations for hazardous materials. For export inquiries, please contact TSS directly.
How can I request a quote or sample for Glyoxylic acid monohydrate?
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To request a quote or sample, please contact our sales department via the website or direct email, providing your specific requirements.
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