Glyoxal sodium bisulfite addition compound hydrate
Glyoxal sodium bisulfite addition compound hydrate (CAS 332360-05-1), with the linear formula [-CH(OH)SO3Na]2 · xH2O, is a hydrate of the disodium salt of the addition product of glyoxal and sodium bisulfite. It serves as a valuable intermediate in organic synthesis. This compound is particularly useful as a building block in the chemical synthesis of various organic molecules, including heterocyclic compounds, contributing to advancements in chemical research and development.
- IUPAC
- 1,2-Dihydroxy-1,2-ethanedisulfonic acid disodium salt hydrate
- Synonyms
- 1,2-Dihydroxy-1,2-ethanedisulfonic acid disodium salt hydrate
![Glyoxal sodium bisulfite addition compound hydrate ([-CH(OH)SO3Na]2 · xH2O) — chemical structure, CAS 332360-05-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F332360-05-1.png&w=3840&q=75)
Synthesis of Indole Derivatives
This compound has been employed in the conversion of substituted anilines to indole derivatives, facilitating the formation of complex heterocyclic structures.
Quinoxaline Synthesis
It has been utilised as a reagent in the synthesis of quinoxaline structures, which are important scaffolds in medicinal chemistry and materials science.
Organic Synthesis Intermediate
As a versatile building block, it plays a role in the construction of diverse organic molecules, supporting various chemical synthesis pathways.
| Molecular weight | 266.16 (anhydrous basis) |
|---|---|
| Linear formula | [-CH(OH)SO3Na]2 · xH2O |
| Application | Glyoxal sodium bisulfite addition compound hydrate was used to convert N-benzyl-2,3,4-trimethoxyaniline to sodium 5,6,7-trimethoxy-1-benzylindolyl-2-sulfite1. It was used in the synthesis of 6-hydroxyquinoxaline2. |
| Melting point | 193 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glyoxal sodium bisulfite addition compound hydrate used for?
+
Glyoxal sodium bisulfite addition compound hydrate is used as a building block in chemical synthesis, particularly for creating indole and quinoxaline derivatives, and other organic molecules.
What is the CAS number and chemical formula for Glyoxal sodium bisulfite addition compound hydrate?
+
The CAS number is 332360-05-1, and the linear formula is [-CH(OH)SO3Na]2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound as a technical or research grade chemical. We do not represent it as USP, BP, or EP grade.
How should Glyoxal sodium bisulfite addition compound hydrate be handled?
+
Handle with appropriate personal protective equipment, including a dust mask (e.g., N95), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
What are the primary hazards associated with this compound?
+
This compound is classified with GHS07, presenting a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions handles packing, shipping, and exporting in compliance with international regulations for chemical substances, ensuring safe and efficient delivery globally.
How can I request a sample or quote for Glyoxal sodium bisulfite addition compound hydrate?
+
To request a sample or quote, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis