Glycine tert-butyl ester hydrochloride
Glycine tert-butyl ester hydrochloride (CAS: 27532-96-3) is a protected amino acid derivative with the molecular formula H₂NCH₂CO₂C(CH₃)₃ · HCl and a molecular weight of 167.63 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of complex organic molecules. Its structure features a tert-butyl ester protecting group on the glycine carboxyl, facilitating controlled reactions.
- IUPAC
- tert-Butyl aminoacetate hydrochloride
- Synonyms
- tert-Butyl aminoacetate hydrochloride
Peptide Synthesis
Glycine tert-butyl ester hydrochloride is employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. The tert-butyl ester group offers orthogonal protection strategies, allowing for selective deprotection under acidic conditions.
Organic Synthesis Intermediate
This compound acts as a versatile intermediate in the synthesis of various organic molecules, including pharmaceuticals and biologically active compounds. It enables the introduction of a protected glycine moiety into target structures.
Chemical Biology Research
Researchers utilise Glycine tert-butyl ester hydrochloride in chemical biology to construct modified peptides or probes for studying biological processes. Its defined structure aids in creating tools for molecular investigation.
| Molecular weight | 167.63 |
|---|---|
| Linear formula | H2NCH2CO2C(CH3)3 · HCl |
| Assay | ≥99.0% (AT) |
| Solubility | H2O: soluble0.1 g/mL, clear, colorless |
| Melting point | 141-143 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycine tert-butyl ester hydrochloride used for?
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Glycine tert-butyl ester hydrochloride is primarily used as a building block in peptide synthesis and as an intermediate in the preparation of other organic compounds, particularly in pharmaceutical and chemical biology research.
What is the CAS number and formula for Glycine tert-butyl ester hydrochloride?
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The CAS number is 27532-96-3 and the chemical formula is H₂NCH₂CO₂C(CH₃)₃ · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Glycine tert-butyl ester hydrochloride with an assay of ≥99.0% (AT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Glycine tert-butyl ester hydrochloride be handled safely?
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When handling Glycine tert-butyl ester hydrochloride, it is essential to use personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use appropriate respiratory protection such as a type N95 (US) or type P1 (EN143) respirator filter.
Is Glycine tert-butyl ester hydrochloride a controlled substance?
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The provided data does not indicate that Glycine tert-butyl ester hydrochloride is a controlled substance.
How is Glycine tert-butyl ester hydrochloride shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, handling shipments and exports in compliance with international regulations.
How can I request a sample or quote for Glycine tert-butyl ester hydrochloride?
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To request a sample or quote, please contact our sales team through the channels provided on the Tech Serve Solutions website.
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