Glycine-15N
Glycine-15N (CAS: 7299-33-4), with the formula H215NCH2CO2H, is an isotopically labeled form of the simplest amino acid, glycine. This compound features a 15N isotope substitution, making it valuable for metabolic studies, NMR spectroscopy, and mass spectrometry. Its primary applications lie in biochemical research for tracing metabolic pathways and in structural biology for protein analysis. Glycine-15N is a crucial reagent for researchers investigating biological systems with enhanced isotopic resolution.
Biochemical Research
Glycine-15N serves as a vital tracer in metabolic studies, allowing researchers to track the fate of glycine within biological systems. Its isotopic enrichment enables precise analysis of metabolic fluxes and pathways using techniques like mass spectrometry.
Nuclear Magnetic Resonance (NMR) Spectroscopy
The 15N enrichment in Glycine-15N enhances NMR signal detection and resolution, making it an excellent probe for studying protein structure, dynamics, and interactions. This is particularly useful in biomolecular NMR applications.
Mass Spectrometry Applications
As a labeled compound, Glycine-15N is indispensable for quantitative mass spectrometry. It acts as an internal standard or is used in metabolic labeling studies (e.g., SILAC variants) to determine protein abundance and identify post-translational modifications.
Peptide and Protein Synthesis
Glycine-15N can be incorporated into synthetic peptides and proteins to facilitate structural or functional studies. This isotopic labeling aids in understanding peptide conformation and protein folding.
| Molecular weight | 76.06 |
|---|---|
| Linear formula | H215NCH2CO2H |
| Melting point | 240 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 76.04 by atom % calculation |
|---|---|
| Isotopic Purity | 98 atom % 15N |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycine-15N used for?
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Glycine-15N is primarily used in biochemical research for metabolic tracing, in NMR spectroscopy for structural studies of biomolecules, and in mass spectrometry for quantitative analysis and metabolic labeling experiments.
What is the CAS number and chemical formula for Glycine-15N?
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The CAS number for Glycine-15N is 7299-33-4, and its chemical formula is H215NCH2CO2H.
What grade and purity does Tech Serve Solutions supply for Glycine-15N?
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Tech Serve Solutions supplies Glycine-15N with a minimum isotopic purity of 98 atom % 15N. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Glycine-15N be handled safely?
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When handling Glycine-15N, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne particles are a concern. Refer to the Safety Data Sheet for full handling instructions.
Is Glycine-15N a controlled substance?
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Based on the provided data, Glycine-15N is not classified as a controlled substance.
How is Glycine-15N packed and shipped?
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Glycine-15N is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Glycine-15N?
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To request a sample or a quotation for Glycine-15N, please contact our sales team through the website or by phone.
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