Glycine ethyl ester hydrochloride
Glycine ethyl ester hydrochloride (CAS: 623-33-6), with the molecular formula NH2CH2COOC2H5 · HCl and a molecular weight of 139.58 g/mol, is an ester derivative of glycine. This compound serves as a valuable building block in organic synthesis, particularly in the preparation of more complex molecules and in peptide chemistry. Its primary applications lie in research and development, offering a reactive intermediate for the synthesis of various chemical entities.
- IUPAC
- Ethyl glycinate hydrochloride
- Synonyms
- Ethyl glycinate hydrochloride

Peptide Synthesis
Glycine ethyl ester hydrochloride is frequently employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, facilitating the formation of peptide bonds.
Organic Synthesis Intermediate
This compound acts as a versatile intermediate for introducing the glycine ethyl ester moiety into various organic structures, enabling the creation of novel compounds for research.
Chemical Biology Research
It is used in chemical biology to develop new probes, modified peptides, or other biologically active molecules for studying cellular processes.
| Molecular weight | 139.58 |
|---|---|
| Linear formula | NH2CH2COOC2H5 · HCl |
| Assay | ≥98.0% (AT) |
| Melting point | 144-148 °C145-146 °C(lit.) |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycine ethyl ester hydrochloride used for?
+
Glycine ethyl ester hydrochloride (CAS: 623-33-6) is primarily used as an intermediate in organic synthesis, especially in peptide chemistry and the preparation of novel chemical entities for research.
What are the CAS number and molecular formula for Glycine ethyl ester hydrochloride?
+
The CAS number is 623-33-6, and the molecular formula is NH2CH2COOC2H5 · HCl.
What grade and purity does Tech Serve Solutions supply for Glycine ethyl ester hydrochloride?
+
Tech Serve Solutions supplies Glycine ethyl ester hydrochloride with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product specifications.
What are the main safety hazards associated with Glycine ethyl ester hydrochloride?
+
Glycine ethyl ester hydrochloride is classified as Danger, with hazard statement H318 indicating it causes serious eye damage. Appropriate personal protective equipment, including eyeshields and gloves, should be used when handling.
Is Glycine ethyl ester hydrochloride available for international export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Glycine ethyl ester hydrochloride, serving customers worldwide.
How can I request a sample or quote for Glycine ethyl ester hydrochloride?
+
Please contact our sales team through the website to request a sample or a quotation for Glycine ethyl ester hydrochloride.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis