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Fluorotrimethylsilane

CAS 420-56-4(CH3)3SiFChemical Synthesis

Fluorotrimethylsilane (CAS 420-56-4), with the linear formula (CH₃)₃SiF and a molecular weight of 92.19 g/mol, is a highly flammable and volatile liquid. It is primarily utilised as a synthetic reagent in organic and organometallic chemistry. Its reactivity makes it valuable for introducing trimethylsilyl groups and as a source of fluoride ions in various chemical transformations. It is supplied with an assay of 96%.

IUPAC
Trimethylfluorosilane,Trimethylsilyl fluoride
Synonyms
TrimethylfluorosilaneTrimethylsilyl fluoride
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Fluorotrimethylsilane ((CH3)3SiF) — chemical structure, CAS 420-56-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisSpecialty GasesSynthetic Reagents
01 /Applications

Fluorinating Agent

Fluorotrimethylsilane serves as a convenient reagent for introducing fluorine atoms into organic molecules. Its controlled reactivity allows for selective fluorination reactions in the synthesis of complex compounds.

Trimethylsilylating Agent

This compound is employed to introduce the trimethylsilyl (TMS) group, which is a common protecting group in organic synthesis. The TMS group can stabilise intermediates or modify the properties of target molecules.

Specialty Gas Applications

Due to its volatility, Fluorotrimethylsilane finds application in processes requiring a gaseous source of trimethylsilyl or fluoride species. Careful handling is essential due to its flammability and potential to release hazardous vapours.

Research and Development

In laboratory settings, Fluorotrimethylsilane is a valuable reagent for exploring new synthetic pathways and developing novel materials. Its unique chemical properties enable diverse research applications.

02 /Properties
Molecular weight92.19
Linear formula(CH3)3SiF
Assay96%
Boiling point16 °C(lit.)
Density0.793 g/mL at 25 °C(lit.)
Melting point−74 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Compressed gas (GHS04)
Compressed gas
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H224Extremely flammable liquid and vapour
  • H280Contains gas under pressure; may explode if heated
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
  • P410Protect from sunlight
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
Flash point-30 °C / -22 °F
Transport (UN / ADR)UN 1954 2.1
Water hazard class (WGK, DE)3
Hazard codes (EU)F+,Xi
Risk statements (R)12-36/37/38
Safety statements (S)9-16-26-33

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
420-56-4
MDL number
MFCD00042064
Beilstein registry
1731132
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fluorotrimethylsilane used for?

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Fluorotrimethylsilane is primarily used as a synthetic reagent in chemical synthesis, including as a fluorinating and trimethylsilylating agent, and for applications requiring a specialty gas.

What is the CAS number and formula for Fluorotrimethylsilane?

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The CAS number is 420-56-4, and the linear formula is (CH₃)₃SiF.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Fluorotrimethylsilane with an assay of 96%. We do not represent this product as meeting any pharmacopoeia standards such as USP, BP, or EP unless explicitly stated.

How should Fluorotrimethylsilane be handled safely?

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Fluorotrimethylsilane is highly flammable and an irritant. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a full-face respirator. Ensure use in a well-ventilated area away from ignition sources, adhering to hazard statements H224, H280, H315, H319, and H335.

How is Fluorotrimethylsilane packed and shipped?

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Fluorotrimethylsilane is packed according to UN 1954 specifications for flammable gases and is exported globally by Tech Serve Solutions.

How can I request a quote or sample?

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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (420-56-4).

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