Flumazenil
Flumazenil (CAS: 78755-81-4), with the molecular formula C15H14FN3O3 and a molecular weight of 303.29 g/mol, is a selective benzodiazepine receptor antagonist. This white crystalline solid is primarily employed in clinical settings to reverse the sedative effects of benzodiazepines. It is a valuable tool in anaesthesia and intensive care, aiding in patient recovery and diagnosis.
- IUPAC
- Ro 15-1788,Ro15-1788
- Synonyms
- Ro 15-1788Ro15-1788
Benzodiazepine Antagonism
Flumazenil functions as a competitive antagonist at the benzodiazepine binding site on the GABA-A receptor complex. This action effectively reverses the central nervous system depressant effects induced by benzodiazepines, such as diazepam or midazolam.
Anesthesia Reversal
In surgical procedures utilizing benzodiazepine-based sedation or anaesthesia, Flumazenil is administered post-operatively to rapidly restore consciousness and respiratory drive in patients. This facilitates quicker recovery and assessment.
Management of Overdosage
It serves as an antidote in cases of suspected or confirmed benzodiazepine overdose, helping to mitigate symptoms like somnolence, respiratory depression, and coma.
| Molecular weight | 303.29 |
|---|---|
| Empirical formula | C15H14FN3O3 |
| Assay | >99% (HPLC) |
| Form | solid |
| Colour | white |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Flumazenil used for?
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Flumazenil (CAS: 78755-81-4) is used to reverse the sedative effects of benzodiazepines and to manage benzodiazepine overdose. Its chemical formula is C15H14FN3O3.
What is the CAS number and chemical formula for Flumazenil?
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The CAS number for Flumazenil is 78755-81-4 and its chemical formula is C15H14FN3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Flumazenil with a purity of >99% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Flumazenil be handled and stored?
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Handle Flumazenil with appropriate personal protective equipment, including eyeshields and gloves. Use a P1 or N95 respirator filter if needed. It should be stored at 2-8°C.
Is Flumazenil a controlled substance?
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The provided data does not indicate that Flumazenil is a controlled substance. For specific regulatory information, please consult local authorities.
How are Flumazenil products packed and exported?
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Flumazenil is typically supplied as a solid. Tech Serve Solutions is a global supplier and exporter, adhering to international shipping regulations.
How can I request a quote or sample of Flumazenil?
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To request a quote or sample for Flumazenil, please contact the Tech Serve Solutions sales team through our website or by phone.
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