Ethylmagnesium chloride solution
Ethylmagnesium chloride solution (CAS: 2386-64-3; Linear Formula: CH<sub>3</sub>CH<sub>2</sub>MgCl; Molar Mass: 88.82) is a vital Grignard reagent offered by Tech Serve Solutions. It is supplied as a 2.0 M solution in tetrahydrofuran (THF). This organometallic compound is a cornerstone in organic synthesis, widely employed for carbon-carbon bond formation in the production of pharmaceuticals, fine chemicals, and various complex organic molecules.
Carbon-Carbon Bond Formation
Ethylmagnesium chloride solution serves as a potent nucleophile in Grignard reactions, enabling the formation of new carbon-carbon bonds. This is a fundamental transformation in the synthesis of complex organic molecules, including pharmaceutical intermediates.
Synthesis of Alcohols
Reacting ethylmagnesium chloride with aldehydes or ketones leads to the formation of secondary or tertiary alcohols, respectively. This is a widely used method for introducing ethyl groups and constructing more elaborate molecular frameworks.
Alkylation Reactions
As a strong base and nucleophile, this Grignard reagent can be used to alkylate various electrophilic substrates. It is a versatile tool for introducing ethyl functional groups into organic compounds.
| Molecular weight | 88.82 |
|---|---|
| Linear formula | CH3CH2MgCl |
| Density | 0.978 g/mL at 25 °C |
| Concentration | 2.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-17-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethylmagnesium chloride solution used for?
+
Ethylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis for the formation of carbon-carbon bonds and the synthesis of alcohols and other ethyl-substituted compounds. It is a key reagent in the production of fine chemicals and pharmaceutical intermediates.
What is the CAS number and formula for Ethylmagnesium chloride solution?
+
The CAS number is 2386-64-3, and the linear formula is CH<sub>3</sub>CH<sub>2</sub>MgCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Ethylmagnesium chloride solution at a concentration of 2.0 M in THF. The specific purity and grade are available upon request, and it is supplied for research and laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should Ethylmagnesium chloride solution be handled?
+
Ethylmagnesium chloride solution is highly flammable and reacts violently with water, potentially forming explosive peroxides. It is corrosive and can cause severe skin burns and eye damage, and may cause respiratory irritation. Always handle under an inert atmosphere, wear appropriate personal protective equipment including gloves, eye protection, and a suitable respirator, and avoid contact with water, air, and incompatible materials. Store in a cool, well-ventilated area away from ignition sources.
Is Ethylmagnesium chloride solution regulated?
+
This product is classified under UN 3399, Hazard Class 4.3 (Dangerous when wet substances) and Packing Group I, indicating a high danger. Please consult local regulations for specific handling and transport requirements.
How are Ethylmagnesium chloride solutions typically packed and shipped?
+
Ethylmagnesium chloride solutions are carefully packed in specialised containers designed for hazardous and flammable materials, often under an inert atmosphere. TSS exports globally, adhering to all international shipping regulations for hazardous chemicals.
How can I request a quote or sample for Ethylmagnesium chloride solution?
+
To request a quote or a sample of Ethylmagnesium chloride solution, please contact our sales team via the website or directly by phone. Please specify the quantity and any particular requirements you may have.
▶ Related products
5-Sulfosalicylic acid dihydrate
HO3SC6H3-2-(OH)CO2H 2H2O
Acids & Bases
Calcium hydroxide
Ca(OH)2
Acids & Bases
Acetic acid-12C2
12CH312CO2H
Acids & Bases
Acetic acid-13C2
13CH313CO2H
Acids & Bases
Acetic acid-13C2,d4
Acids & Bases
Acetic acid-17O2
CH3C17O2H
Acids & Bases
Acetic acid-18O2
CH3C18O2H
Acids & Bases
Acetic acid-2,2,2-d3
2-d3
Acids & Bases▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis