Ethyllithium solution
Ethyllithium solution (CAS 811-49-4), with the chemical formula CH3CH2Li and a molecular weight of 36.00 g/mol, is a highly reactive organometallic compound. Supplied as a solution in benzene:cyclohexane at 0.5 M, it serves as a potent base and nucleophile in organic synthesis. Its primary applications involve introducing ethyl groups and facilitating deprotonation reactions in the formation of complex organic molecules.
Organolithium Reagent
Ethyllithium is a versatile organolithium reagent used in organic synthesis for alkylation reactions and as a strong base for deprotonation.
Deprotonation Agent
Its strong basicity makes it effective for removing acidic protons, facilitating carbanion formation essential for C-C bond formation.
Nucleophilic Addition
As a nucleophile, ethyllithium readily adds to electrophilic centers such as carbonyl groups, epoxides, and imines.
Intermediate Synthesis
It is employed in the synthesis of various pharmaceutical intermediates and complex organic compounds where precise ethyl group introduction is required.
| Molecular weight | 36.00 |
|---|---|
| Linear formula | CH3CH2Li |
| Density | 0.862 g/mL at 25 °C |
| Concentration | 0.5 M in benzene: cyclohexane |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H304May be fatal if swallowed and enters airways
- H315Causes skin irritation
- H319Causes serious eye irritation
- H340May cause genetic defects
- H350May cause cancer
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P201Obtain special instructions before use
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P273Avoid release to the environment
- P301IF SWALLOWED
- P422
| Flash point | -27 °C / -16.6 °F |
|---|---|
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T,N |
| Risk statements (R) | 45-46-11-36/38-48/23/24/25-50/53-65 |
| Safety statements (S) | 53-16-26-45-61-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyllithium solution used for?
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Ethyllithium solution is used as a potent base and nucleophile in organic synthesis, particularly for alkylation, deprotonation, and in the synthesis of pharmaceutical intermediates and complex organic molecules.
What is the CAS number and chemical formula for Ethyllithium solution?
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The CAS number is 811-49-4 and the chemical formula is CH3CH2Li.
What grade and purity does Tech Serve Solutions supply for Ethyllithium solution?
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Tech Serve Solutions supplies Ethyllithium solution at a concentration of 0.5 M in benzene:cyclohexane. We do not claim USP, BP, or EP grade; this product is intended for laboratory and research purposes.
How should Ethyllithium solution be handled and stored?
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Ethyllithium solution is highly flammable, pyrophoric, and reacts violently with water. It is also corrosive and poses serious health risks, including carcinogenicity and mutagenicity. Handle under an inert atmosphere (e.g., nitrogen or argon) and store at 2-8°C in its Sure/Seal™ container.
Is Ethyllithium solution flammable?
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Yes, Ethyllithium solution is highly flammable (Flash Point: -27 °C) and must be handled with extreme caution away from ignition sources.
How is Ethyllithium solution packed, shipped, and exported?
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Ethyllithium solution is supplied in 25mL Sure/Seal™ reagents containers under an inert atmosphere. TSS is a global supplier and exporter of fine chemicals, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for Ethyllithium solution?
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Please contact our sales department via our website or telephone to request a sample or a detailed quotation for Ethyllithium solution.
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