Ethylene di(p-toluenesulfonate)
Ethylene di(p-toluenesulfonate) (CAS 6315-52-2) is a difunctional organic compound with the formula [CH3C6H4SO3CH2-]2 and a molecular weight of 370.44 g/mol. This tosylate ester serves as a versatile building block in organic synthesis. Its primary applications include the preparation of complex macrocyclic structures and fused ring systems, contributing to advancements in supramolecular chemistry and the development of novel molecular architectures.
- IUPAC
- Ethylene ditosylate,Ethylene glycol ditosylate
- Synonyms
- Ethylene glycol ditosylateEthylene ditosylate
![Ethylene di(p-toluenesulfonate) ([CH3C6H4SO3CH2-]2) — chemical structure, CAS 6315-52-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F6315-52-2.png&w=3840&q=75)
Synthesis of Macrocyclic Ligands
Ethylene di(p-toluenesulfonate) is employed in the synthesis of complex macrocyclic compounds such as cyclohexyl-fused 1,4,7-triazacyclononane. These molecules are valuable in coordination chemistry and host-guest complexation studies.
Preparation of Calixarene Derivatives
This compound is a key reagent for the synthesis of various calixarene derivatives, including ethylene-bridged calixarenes and calixarene-crown ethers. These are utilized in areas like ion recognition and sensing.
Organic Synthesis Intermediate
As a difunctional electrophile, Ethylene di(p-toluenesulfonate) acts as a useful building block in constructing larger organic molecules. It facilitates the introduction of ethylene linkers in various synthetic pathways.
| Molecular weight | 370.44 |
|---|---|
| Linear formula | [CH3C6H4SO3CH2-]2 |
| Assay | 97% |
| Application | Ethylene di(p-toluenesulfonate) [Ethylene glycol ditosylate] has been used in the synthesis of:• cyclohexyl-fused 1,4,7-triazacyclononane1• 1,2-ethylenecalix[6]arene, 1,3- and 1,4-calix[6]crown-3, 1,3- and 1,4-calix[6]crown-4, 1,4-calix[6]benzocrown-4, 1,2- and 1,3-calix[6]crown-52 |
| Melting point | 124-127 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethylene di(p-toluenesulfonate) used for?
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Ethylene di(p-toluenesulfonate) is used as a building block in organic synthesis, particularly for creating macrocyclic structures and calixarene derivatives.
What are the CAS number and formula for Ethylene di(p-toluenesulfonate)?
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The CAS number is 6315-52-2, and the formula is [CH3C6H4SO3CH2-]2.
What grade and purity does Tech Serve Solutions supply for Ethylene di(p-toluenesulfonate)?
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Tech Serve Solutions supplies Ethylene di(p-toluenesulfonate) with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethylene di(p-toluenesulfonate) be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified with Warning signal word and H315-H319-H335 hazard statements.
Is Ethylene di(p-toluenesulfonate) available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Ethylene di(p-toluenesulfonate), and can fulfil export orders.
How can I request a quote or sample for Ethylene di(p-toluenesulfonate)?
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To request a quote or sample, please contact our sales team through the website or by phone. Please provide the product name and CAS number (6315-52-2) for prompt service.
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