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Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate

CAS 84028-88-6CH3CH(OSO2CF3)CO2C2H5Chemical Synthesis

Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate (CAS: 84028-88-6), with the chemical formula CH3CH(OSO2CF3)CO2C2H5 and a molecular weight of 250.19 g/mol, is a chiral triflate ester. It serves as a valuable intermediate in organic synthesis, particularly in asymmetric reactions. Its structure makes it suitable for introducing chiral centres and for use in complex molecule construction within chemical research and development.

IUPAC
Ethyl O-trifluoromethanesulfonyl-L-lactate,Ethyl L-lactate 2-O-triflate
Synonyms
Ethyl O-trifluoromethanesulfonyl-L-lactateEthyl L-lactate 2-O-triflate
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Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate (CH3CH(OSO2CF3)CO2C2H5) — chemical structure, CAS 84028-88-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksEstersOrganic Building Blocks
01 /Applications

Chiral Building Block

Utilised as a stereodefined building block in the synthesis of complex chiral molecules. Its triflate leaving group facilitates various coupling and substitution reactions.

Asymmetric Synthesis

A key reagent in asymmetric synthesis, enabling the creation of enantiomerically enriched compounds crucial for pharmaceuticals and agrochemicals.

Organic Synthesis Intermediate

Serves as a versatile intermediate in multi-step organic synthesis pathways, offering a reactive chiral centre for further chemical transformations.

02 /Properties
Molecular weight250.19
Linear formulaCH3CH(OSO2CF3)CO2C2H5
Assay≥96%
Boiling point34 °C/0.005 mmHg(lit.)
Density1.342 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.374(lit.)
Optical activity[α]20/D −44°, neat
Storage temperature−20°C
Contains / stabiliser~1% MgO as stabilizer
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point79 °C / 174.2 °F
Transport (UN / ADR)UN 3265 8 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
84028-88-6
MDL number
MFCD00134396
PubChem substance
24889539
Beilstein registry
3549394
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate used for?

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Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate (CAS: 84028-88-6) is primarily used as a chiral building block and intermediate in asymmetric organic synthesis.

What are the CAS number and chemical formula for this product?

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The CAS number is 84028-88-6 and the chemical formula is CH3CH(OSO2CF3)CO2C2H5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate with an assay of ≥96%. This product is not supplied as USP, BP, EP, or any pharmacopoeia grade.

What are the safety considerations for handling this chemical?

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This compound is classified with GHS symbol GHS05 and signal word Danger, indicated by hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, must be worn. Handle only in well-ventilated areas and follow all safety precautions.

How is this chemical shipped and exported?

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Ethyl (S)-2-(trifluoromethylsulfonyloxy)propionate is shipped according to UN 3265, Class 8, Packing Group III regulations. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.

How can I request a sample or quote?

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To request a sample or obtain a quotation, please contact our sales team through the website or by phone, referencing product CAS 84028-88-6.

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