2-Chloro-1,3,2-dioxaphospholane 2-oxide
2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS 6609-64-9), with the empirical formula C2H4ClO3P and a molecular weight of 142.48 g/mol, is a chemical compound primarily utilised as a phosphorylating agent. Its key application lies in organic synthesis, specifically in the preparation of phosphatidylcholines. It is supplied by Tech Serve Solutions with an assay of ≥95.0% (NMR).
- IUPAC
- 2-Chloro-2-oxo-1,3,2-dioxaphospholane,Ethylene glycol chlorophosphate
- Synonyms
- 6609-64-9C2H4ClO3P2-Chloro-2-oxo-1,3,2-dioxaphospholaneEthylene glycol chlorophosphate
Phosphorylating Agent
This compound serves as an effective phosphorylating agent in various organic synthesis pathways. It is particularly noted for its use in the construction of complex molecules.
Synthesis of Phosphatidylcholines
A specific and important application of 2-Chloro-1,3,2-dioxaphospholane 2-oxide is in the synthesis of phosphatidylcholines. These are vital components found in biological membranes.
Organic Building Block
As a functionalised organophosphorus compound, it acts as a versatile building block in organic chemistry, enabling the introduction of specific phosphorus-containing moieties into target molecules.
| Molecular weight | 142.48 |
|---|---|
| Empirical formula | C2H4ClO3P |
| Assay | ≥95.0% (NMR) |
| Boiling point | 89-91 °C/0.8 mmHg(lit.) |
| Density | 1.55 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.45(lit.) |
| Storage temperature | −20°C |
| Melting point | 12-14 °C (neat)(lit.) |
| Impurities tested | <10% 2-Chloro-1,3,2-dioxaphospholane |
| Application | Phosphorylating agent used in the syntheses of phosphatidylcholines.1,2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-1,3,2-dioxaphospholane 2-oxide used for?
+
2-Chloro-1,3,2-dioxaphospholane 2-oxide is primarily used as a phosphorylating agent in organic synthesis, notably for the preparation of phosphatidylcholines.
What are the CAS number and formula for 2-Chloro-1,3,2-dioxaphospholane 2-oxide?
+
The CAS number is 6609-64-9, and its empirical formula (Hill notation) is C2H4ClO3P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Chloro-1,3,2-dioxaphospholane 2-oxide with an assay of ≥95.0% (NMR). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Chloro-1,3,2-dioxaphospholane 2-oxide be handled safely?
+
This compound is classified as corrosive and reacts violently with water. Handling requires stringent safety measures, including appropriate personal protective equipment such as full-face respirators, gloves, and goggles, and should be performed in a well-ventilated area away from water. Refer to the safety data sheet for comprehensive guidelines.
Is 2-Chloro-1,3,2-dioxaphospholane 2-oxide available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Chloro-1,3,2-dioxaphospholane 2-oxide, adhering to all international shipping regulations.
How can I request a sample or quote for this chemical?
+
To request a sample or a quote for 2-Chloro-1,3,2-dioxaphospholane 2-oxide, please contact our sales department through the website or by direct inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis