2-Chloro-1,1,1-trimethoxyethane
2-Chloro-1,1,1-trimethoxyethane (CAS 74974-54-2) is a liquid organic compound with the molecular formula ClCH₂C(OCH₃)₃ and a molecular weight of 154.59 g/mol. This ortho ester, characterized by its acetal functional group, serves as a versatile building block in organic synthesis. It is primarily utilised in chemical research and development for the construction of more complex molecules, particularly within the pharmaceutical and fine chemical sectors.
- IUPAC
- Trimethyl chloro-orthoacetate
- Synonyms
- 74974-54-2ClCH2C(OCH3)3Trimethyl chloro-orthoacetate
Organic Synthesis Intermediate
2-Chloro-1,1,1-trimethoxyethane functions as a valuable intermediate in multi-step organic syntheses. Its structure allows for various chemical transformations, enabling the introduction of specific functionalities into target molecules.
Building Block for Heterocycles
The compound can be employed in the construction of heterocyclic compounds, which are prevalent motifs in pharmaceuticals and agrochemicals. Its reactivity profile supports its use in ring-forming reactions.
Reagent in Fine Chemical Production
Utilized in the synthesis of fine chemicals, this reagent contributes to the development of specialised materials and advanced chemical products. Its purity is critical for ensuring successful synthetic outcomes.
| Molecular weight | 154.59 |
|---|---|
| Linear formula | ClCH2C(OCH3)3 |
| Assay | 98% |
| Boiling point | 138 °C(lit.) |
| Density | 1.147 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.425(lit.) |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10 |
| Safety statements (S) | 16-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-1,1,1-trimethoxyethane primarily used for?
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2-Chloro-1,1,1-trimethoxyethane is used as a building block and intermediate in organic synthesis, particularly in the production of fine chemicals and pharmaceutical intermediates.
What are the CAS number and chemical formula for 2-Chloro-1,1,1-trimethoxyethane?
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The CAS number is 74974-54-2 and the linear formula is ClCH₂C(OCH₃)₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-1,1,1-trimethoxyethane with an assay of 98%. This is a technical grade material and TSS does not represent it as USP, BP, or EP grade.
How should 2-Chloro-1,1,1-trimethoxyethane be handled safely?
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2-Chloro-1,1,1-trimethoxyethane is a flammable liquid (H226). Handling requires appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves. Ensure adequate ventilation and avoid sources of ignition.
Is 2-Chloro-1,1,1-trimethoxyethane controlled or scheduled?
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The provided data does not indicate that 2-Chloro-1,1,1-trimethoxyethane is a controlled or scheduled substance.
How is 2-Chloro-1,1,1-trimethoxyethane shipped and exported?
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2-Chloro-1,1,1-trimethoxyethane is shipped and exported under UN 1993, Classification C3, Packing Group III, adhering to relevant transport regulations for flammable liquids.
How can I request a sample or quote for 2-Chloro-1,1,1-trimethoxyethane?
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To request a sample or quote, please contact the Tech Serve Solutions sales department through the website or by phone.
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