Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate
Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate (CAS: 106513-42-2) is a chiral building block with the molecular formula CH3CH[OSi(CH3)2C(CH3)3]CO2C2H5 and a molecular weight of 232.39 g/mol. This ester is primarily utilised as a precursor in asymmetric synthesis, notably in the creation of the side chain for didemnin B and in the synthesis of functionalised 1,2-diols. Supplied by Tech Serve Solutions, it offers high purity for advanced chemical research and development.
![Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate (CH3CH[OSi(CH3)2C(CH3)3]CO2C2H5) — chemical structure, CAS 106513-42-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F106513-42-2.png&w=3840&q=75)
Precursor for Didemnin B Side Chain Synthesis
Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate serves as a key intermediate in the synthesis of the lactyl-3,4-didehydroproline didemnin B side chain, contributing to the development of complex molecules.
Asymmetric Synthesis of Diols
This chiral compound is an important starting material for the asymmetric synthesis of both syn- and anti-functionalised 1,2-diols, enabling stereoselective preparation of valuable chemical entities.
Chiral Building Block
As a versatile chiral building block, it is instrumental in constructing stereochemically defined molecules, finding application across various fields of organic synthesis and medicinal chemistry.
| Molecular weight | 232.39 |
|---|---|
| Linear formula | CH3CH[OSi(CH3)2C(CH3)3]CO2C2H5 |
| Assay | 98% |
| Boiling point | 187 °C(lit.) |
| Density | 0.875 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.425(lit.) |
| Optical activity | [α]20/D −30°, c = 1.26 in chloroform |
| Application | Precursor to the lactyl-3,4-didehydroproline didemnin B side chain.1 Starting material for the asymmetric synthesis of syn- and anti- functionalized1,2-diols.2 |
| Flash point | 79 °C / 174.2 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate used for?
+
Ethyl (S)-(−)-2-(tert-butyldimethylsilyloxy)propionate is used as a precursor for the didemnin B side chain and as a starting material in the asymmetric synthesis of 1,2-diols.
What is the CAS number and molecular formula?
+
The CAS number is 106513-42-2 and the molecular formula is CH3CH[OSi(CH3)2C(CH3)3]CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product at a purity of 98%. This is a research grade chemical and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How is this chemical classified for transport?
+
This chemical is classified as NA 1993 / PGIII for transport purposes.
What are the main safety considerations for handling this chemical?
+
This chemical has a flash point of 79 °C (174.2 °F) and should be handled with appropriate precautions to avoid ignition sources.
How can I request a quote or sample?
+
Please contact our sales team via the website or by phone to request a quotation or to arrange for a sample.
Is this chemical exported?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis