3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal
3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal (CAS: 111830-53-6) is a key carbohydrate derivative with a molecular weight of 374.66 g/mol. This silyl-protected glucal serves as a crucial building block in organic synthesis, particularly for the construction of complex oligosaccharide structures. Its protected hydroxyl groups enable selective manipulation in both solution-phase and solid-phase synthetic strategies, facilitating advancements in glycochemistry.
- Synonyms
- C18H38O4Si2

Oligosaccharide Synthesis
Serves as an essential intermediate for the synthesis of complex oligosaccharides. Its protected form allows for controlled glycosylation reactions, vital in the development of carbohydrate-based therapeutics and glycoconjugates.
Glycochemistry Research
A valuable reagent in academic and industrial research for exploring novel glycosylation methodologies. Facilitates the creation of diverse carbohydrate scaffolds for biological studies.
Carbohydrate Derivative Preparation
Used as a precursor for synthesising various modified carbohydrates. The tert-butyldimethylsilyl groups offer selective protection and deprotection strategies in multi-step synthetic routes.
| Molecular weight | 374.66 |
|---|---|
| Empirical formula | C18H38O4Si2 |
| Assay | 97% |
| Optical activity | [α]20/D −44°, c = 0.9 in chloroform |
| Application | Important building block for both solution- and solid-phase synthesis of oligosaccharides.1 |
| Melting point | 43-45 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal used for?
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3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal is primarily used as an important building block for both solution- and solid-phase synthesis of oligosaccharides.
What is the CAS number and molecular formula for this compound?
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The CAS number is 111830-53-6, and the empirical formula (Hill notation) is C18H38O4Si2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling considerations for this chemical?
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This compound has a WGK Germany rating of 3, indicating it is hazardous. Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a flash point above 113 °C (235.4 °F).
How is this product packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports fine chemicals globally, adhering to all relevant regulations to ensure safe and compliant delivery.
How can I request a sample or quote for 3,6-Di-O-(tert-butyldimethylsilyl)-D-glucal?
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To request a sample or a quote, please contact our sales team directly through our website or by calling us. Please have the product name and CAS number ready.
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