Ethyl iodoacetate
Ethyl iodoacetate (CAS: 623-48-3) is a valuable organic compound with the linear formula ICH₂COOC₂H₅ and a molecular weight of 214.00 g/mol. This ester serves as a crucial building block and reagent in chemical synthesis. Its reactivity makes it useful for introducing the iodoacetyl group in various organic transformations, contributing to the creation of complex molecules within the pharmaceutical and fine chemical industries.

Organic Synthesis Reagent
Ethyl iodoacetate is frequently employed as an alkylating agent in organic synthesis. It is particularly useful for introducing the ethoxycarbonylmethyl group into nucleophilic substrates, facilitating the construction of carbon-carbon and carbon-heteroatom bonds.
Pharmaceutical Intermediate
This compound acts as a key intermediate in the synthesis of various pharmaceutical agents. Its structure allows for versatile derivatization, enabling the development of novel drug candidates and the optimization of synthetic routes for existing medicines.
Fine Chemical Manufacturing
Within the fine chemical sector, ethyl iodoacetate is utilized in the production of specialized chemicals. Its controlled reactivity is essential for processes requiring precise chemical modifications and the synthesis of high-purity target molecules.
| Molecular weight | 214.00 |
|---|---|
| Linear formula | ICH2COOC2H5 |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 179-180 °C(lit.) |
| Density | 1.808 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.503(lit.)n20/D 1.506 |
| Storage temperature | 2-8°C |


Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | UN 2922 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl Iodoacetate primarily used for?
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Ethyl iodoacetate is primarily used as an alkylating agent and a building block in organic synthesis, particularly in the pharmaceutical and fine chemical industries.
What are the CAS number and linear formula for Ethyl Iodoacetate?
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The CAS number for Ethyl Iodoacetate is 623-48-3, and its linear formula is ICH₂COOC₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl Iodoacetate with a purity of ≥98.0% (GC) as a purum grade. We do not represent this product as USP, BP, or EP grade.
How should Ethyl Iodoacetate be handled safely?
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Ethyl Iodoacetate is a dangerous substance that causes severe skin burns and eye damage and is toxic if swallowed. Handle with extreme caution, wearing appropriate personal protective equipment including full-face shields, gloves, and respirators. Ensure adequate ventilation and refer to the Safety Data Sheet for comprehensive handling guidelines.
How is Ethyl Iodoacetate packed, shipped, and exported?
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Ethyl Iodoacetate is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions, as a global supplier and exporter, ensures compliance with all necessary transport and customs requirements for worldwide distribution.
How can I request a sample or quote for Ethyl Iodoacetate?
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To request a sample or a quote for Ethyl Iodoacetate, please contact our sales department directly through the website or by phone. Our team will be pleased to assist you with your specific requirements.
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