Ethyl isocyanatoacetate
Ethyl isocyanatoacetate (CAS: 2949-22-6) is an organic compound with the linear formula OCNCH₂COOCH₂CH₃ and a molecular weight of 129.11 g/mol. This isocyanate derivative serves as a valuable building block in chemical synthesis. Its applications include the preparation of complex organic molecules and intermediates, contributing to advancements in various chemical research and development sectors.
Preparation of Nicotine Immunogens
Ethyl isocyanatoacetate is utilized in the synthesis of 6-(carboxymethylureido)-(±)-nicotine (CMUNic), a compound employed as an immunogen for research purposes related to nicotine studies.
Synthesis of Heterocyclic Compounds
This reagent has been employed in the construction of complex heterocyclic systems, such as ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate.
Intermediate for Imidazoquinazoline Derivatives
It serves as a precursor in the synthesis of compounds like imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione, contributing to the development of novel chemical entities.
| Molecular weight | 129.11 |
|---|---|
| Linear formula | OCNCH2COOCH2CH3 |
| Assay | 95% |
| Boiling point | 67-68 °C/11 mmHg(lit.) |
| Density | 1.151 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.) |
| Impurities tested | <5% N-(chloroformyl)glycine ethyl ester |
| Application | Ethyl isocyanatoacetate has been used in the preparation of:• 6-(carboxymethylureido)-(±)-nicotine (CMUNic), nicotine immunogen1• ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate2• imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl isocyanatoacetate used for?
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Ethyl isocyanatoacetate is primarily used as a building block in chemical synthesis for preparing various organic compounds, including specific immunogens and heterocyclic derivatives.
What is the CAS number and formula for Ethyl isocyanatoacetate?
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The CAS number for Ethyl isocyanatoacetate is 2949-22-6, and its linear formula is OCNCH₂COOCH₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl isocyanatoacetate with an assay of 95%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Ethyl isocyanatoacetate be handled safely?
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Ethyl isocyanatoacetate is a hazardous substance. It is harmful if swallowed, causes skin and eye irritation, may cause an allergic skin reaction, and can cause respiratory irritation and symptoms of allergy or asthma or breathing difficulties if inhaled. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
How is Ethyl isocyanatoacetate packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all necessary regulations for safe packing and transportation of hazardous materials.
How can I request a sample or quote for Ethyl isocyanatoacetate?
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Please contact our sales department via the website or by phone to request a sample or a quotation for Ethyl isocyanatoacetate.
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