Ethyl chlorooxoacetate
Ethyl chlorooxoacetate (CAS 4755-77-5) is a key chemical intermediate with the linear formula ClCOCOOCH2CH3 and a molecular weight of 136.53 g/mol. It functions as a versatile reagent in organic synthesis, particularly for introducing the ethoxycarbonyl group. Its reactivity makes it valuable in the preparation of various complex organic molecules and pharmaceutical building blocks. Available from Tech Serve Solutions with a purity of 98%, it is supplied for laboratory and industrial applications.
- IUPAC
- Ethyl chloroglyoxylate,Monoethyl oxalyl chloride,Oxalic acid monoethyl ester chloride,mono-Ethyl oxalyl chloride
Organic Synthesis Reagent
Ethyl chlorooxoacetate is extensively used as an acylating agent in organic chemistry. It facilitates the synthesis of esters, amides, and heterocyclic compounds, serving as a crucial building block for more complex molecules.
Pharmaceutical Intermediate
This compound acts as a valuable intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its reactive chlorooxoacetyl group allows for controlled introduction of specific functionalities required in drug development.
Chemical Research
Utilised in academic and industrial research settings for developing novel synthetic pathways and exploring new chemical entities. Its predictable reactivity is beneficial for process development and optimisation.
| Molecular weight | 136.53 |
|---|---|
| Linear formula | ClCOCOOCH2CH3 |
| Assay | 98% |
| Boiling point | 135 °C(lit.) |
| Density | 1.222 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 41 °C / 105.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl chlorooxoacetate used for?
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Ethyl chlorooxoacetate (CAS 4755-77-5) is primarily used as a reagent in organic synthesis, particularly for acylation reactions and as an intermediate in the preparation of pharmaceuticals and complex organic molecules.
What are the CAS number and formula for Ethyl chlorooxoacetate?
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The CAS number for Ethyl chlorooxoacetate is 4755-77-5. Its linear formula is ClCOCOOCH2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl chlorooxoacetate with an assay of 98%. This product is intended for chemical synthesis and research purposes and is not represented as USP, BP, or EP grade.
How should Ethyl chlorooxoacetate be handled safely?
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Ethyl chlorooxoacetate is a dangerous substance (GHS02, GHS05, Signal Word: Danger, H226-H314). It is flammable and causes severe skin burns and eye damage. Handle with extreme care, using appropriate personal protective equipment including gloves, goggles, a faceshield, and a suitable respirator, in a well-ventilated area.
Is Ethyl chlorooxoacetate flammable?
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Yes, Ethyl chlorooxoacetate is flammable, with a flash point of 41 °C (105.8 °F) (H226).
How is Ethyl chlorooxoacetate packed and shipped?
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Ethyl chlorooxoacetate is packed and shipped in accordance with international regulations for hazardous materials (UN 2920, PGII), ensuring safe transport globally.
How can I request a quote or sample for Ethyl chlorooxoacetate?
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To request a quote or sample for Ethyl chlorooxoacetate, please contact our sales department through the TSS website or direct email, providing your specific requirements.
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