Ethyl azidoacetate solution
Ethyl azidoacetate solution (CAS: 637-81-0), with the molecular formula N₃CH₂COOCH₂CH₃, is a versatile organic compound. Supplied as approximately 30% in methylene chloride, it serves as a valuable building block in organic synthesis and chemical biology. Its azide functional group enables participation in click chemistry reactions and other transformations, making it a key reagent for constructing complex molecules in research and development settings.

Organic Synthesis
Ethyl azidoacetate solution is employed as a reagent in various organic syntheses. Its azide moiety facilitates reactions like the Huisgen cycloaddition, enabling the formation of triazoles and other heterocyclic compounds.
Chemical Biology
This compound is utilized in chemical biology for bioconjugation and labelling applications. It can be incorporated into molecules to introduce an azide handle for subsequent reactions with alkynes or other click chemistry partners.
Research and Development
As a building block, ethyl azidoacetate solution is integral to research laboratories exploring novel synthetic pathways and molecular structures. Its reactivity makes it suitable for creating diverse chemical libraries.
| Molecular weight | 129.12 |
|---|---|
| Linear formula | N3CH2COOCH2CH3 |
| Concentration | ~30% in methylene chloride (NMR) |



Hazard statements
- H225Highly flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
- H315Causes skin irritation
- H336May cause drowsiness or dizziness
- H361D
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 1294 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 63-1-11-38-48/20-65-67 |
| Safety statements (S) | 16-35-36/37-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl azidoacetate solution used for?
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Ethyl azidoacetate solution is used as a building block in organic synthesis and chemical biology, particularly for reactions involving the azide functional group, such as click chemistry.
What is the CAS number and formula for Ethyl azidoacetate solution?
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The CAS number is 637-81-0, and the linear formula is N₃CH₂COOCH₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl azidoacetate solution at approximately 30% in methylene chloride (NMR grade). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethyl azidoacetate solution be handled safely?
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Ethyl azidoacetate solution is flammable and can cause serious health effects. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation and avoid ignition sources. Refer to the Safety Data Sheet for comprehensive guidance.
How is Ethyl azidoacetate solution packed, shipped, and exported?
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Ethyl azidoacetate solution is packed and shipped in compliance with international transportation regulations for hazardous materials, including UN 1294 classification. TSS is experienced in global export.
How can I request a sample or quote for Ethyl azidoacetate solution?
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To request a sample or quote, please contact our sales team via the website or direct inquiry, providing your specific requirements.
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