Ethyl acetimidate hydrochloride
Ethyl acetimidate hydrochloride (CAS: 2208-07-3; Formula: CH3C(=NH)OC2H5 · HCl) is a valuable organic building block supplied by Tech Serve Solutions. With a molecular weight of 123.58 g/mol, this compound serves as a key intermediate in various chemical syntheses. It is primarily utilised in the modification of proteins and the development of novel heterocyclic compounds, making it a useful reagent for research and development in organic chemistry and biochemistry.

Protein Modification
Ethyl acetimidate hydrochloride is employed in the chemical modification of enzymes, such as its use in the amidination of human erythrocyte carbonic anhydrase. This application is crucial for biochemical research and understanding enzyme structure-function relationships.
Heterocyclic Synthesis
This compound acts as a precursor in the synthesis of various heterocyclic structures. For example, it has been used in the preparation of methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride, demonstrating its utility in creating complex organic molecules.
Organic Synthesis Intermediate
As a versatile building block, Ethyl acetimidate hydrochloride is a useful intermediate in general organic synthesis. Its reactivity allows for the introduction of specific functional groups in multi-step synthetic pathways for novel compound development.
| Molecular weight | 123.58 |
|---|---|
| Linear formula | CH3C(=NH)OC2H5 · HCl |
| Assay | 97% |
| Solubility | water: soluble50 mg/mL, clear, colorless |
| Application | Ethyl acetimidate hydrochloride was used in preparation of amidinated carbonic anhydrase via chemical modification of human erythrocyte carbonic anhydrase1. It was also used in synthesis of methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride2. |
| Melting point | 112-114 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl acetimidate hydrochloride used for?
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Ethyl acetimidate hydrochloride is used in applications such as the chemical modification of proteins (e.g., amidination of carbonic anhydrase) and in the synthesis of heterocyclic compounds like methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride.
What is the CAS number and molecular formula for Ethyl acetimidate hydrochloride?
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The CAS number is 2208-07-3, and the molecular formula is CH3C(=NH)OC2H5 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl acetimidate hydrochloride with an assay of 97%. This product is not specified as USP, BP, or EP grade and is intended for research and laboratory use.
How should Ethyl acetimidate hydrochloride be handled safely?
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Ethyl acetimidate hydrochloride is a Warning substance (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes (P305+P351+P338).
Is Ethyl acetimidate hydrochloride packed and shipped by TSS?
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Yes, Tech Serve Solutions, as a specialist global supplier and exporter, packs and ships Ethyl acetimidate hydrochloride according to international standards for chemical distribution.
How can I request a sample or quote for Ethyl acetimidate hydrochloride?
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To request a sample or a quote for Ethyl acetimidate hydrochloride, please contact our sales department through the TSS website or via direct inquiry, providing your specific requirements.
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