Ethyl 2-bromo-4-methylthiazole-5-carboxylate
Ethyl 2-bromo-4-methylthiazole-5-carboxylate (CAS 22900-83-0) is a halogenated heterocyclic compound with the empirical formula C7H8BrNO2S and a molecular weight of 250.11 g/mol. It serves as a valuable building block in organic synthesis, particularly for creating more complex thiazole derivatives. Its structure facilitates various chemical transformations, making it a useful reagent for researchers in medicinal chemistry and materials science exploring novel compounds.

Organic Synthesis Intermediate
This compound is primarily employed as a versatile intermediate in the synthesis of diverse organic molecules. The bromo and ester functionalities allow for a range of derivatization reactions.
Medicinal Chemistry Research
It acts as a key building block for the development of novel pharmaceutical candidates. Thiazole cores are present in many biologically active compounds, making this a relevant precursor.
Materials Science
Researchers may utilise this compound in the exploration of new materials, leveraging its heterocyclic structure for specific electronic or optical properties.
| Molecular weight | 250.11 |
|---|---|
| Empirical formula | C7H8BrNO2S |
| Assay | 97% |
| Melting point | 65-69 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 2-bromo-4-methylthiazole-5-carboxylate used for?
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Ethyl 2-bromo-4-methylthiazole-5-carboxylate (CAS 22900-83-0) is used as a building block and intermediate in organic synthesis, particularly for the preparation of complex thiazole derivatives in medicinal chemistry and materials science research.
What is the CAS number and formula for Ethyl 2-bromo-4-methylthiazole-5-carboxylate?
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The CAS number is 22900-83-0 and the empirical formula is C7H8BrNO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.
How should Ethyl 2-bromo-4-methylthiazole-5-carboxylate be handled?
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Handling requires caution due to its hazardous properties (H315, H317, H318, H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid contact with skin, eyes, and respiratory tract.
Is this chemical packed and shipped internationally?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals.
How can I request a quote or sample?
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Please contact our sales team directly through the website to request a quote or to arrange for a sample.
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