Eserine
Eserine (CAS: 57-47-6), a carbamate alkaloid with the molecular formula C15H21N3O2, is recognised for its potent anticholinesterase activity. It functions by inhibiting the hydrolysis of acetylcholine, thereby increasing cholinergic neurotransmission. This compound is primarily utilized in research settings, particularly within neuroscience and cell biology, to study the mechanisms of neurotransmitter action and enzyme inhibition.
- IUPAC
- Physostigmine
- Synonyms
- Physostigmine
Neuroscience Research
Eserine serves as a valuable tool in neuroscience research to investigate cholinergic pathways and the role of acetylcholine in neurotransmission. Its anticholinesterase properties allow researchers to modulate cholinergic signalling in experimental models.
Enzyme Inhibition Studies
As a well-established acetylcholinesterase inhibitor, Eserine is employed in biochemical assays to study enzyme kinetics and inhibition mechanisms. It helps in understanding the structure-activity relationships of cholinesterase inhibitors.
Cell Biology Investigations
In cell biology, Eserine can be used to explore the effects of enhanced cholinergic activity on cellular functions and signalling pathways. Its application aids in understanding cellular responses to neurotransmitter modulation.
| Molecular weight | 275.35 |
|---|---|
| Empirical formula | C15H21N3O2 |
| Assay | ≥99% (HPLC) |
| Melting point | 102-104 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P284Wear respiratory protection
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/28 |
| Safety statements (S) | 25-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Eserine used for?
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Eserine is primarily used in research settings, particularly within neuroscience and cell biology, to study the mechanisms of neurotransmitter action and enzyme inhibition due to its potent anticholinesterase activity.
What are the CAS number and formula for Eserine?
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The CAS number for Eserine is 57-47-6 and its molecular formula is C15H21N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Eserine with a purity of ≥99% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Eserine be handled safely?
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Eserine is a dangerous substance requiring strict handling precautions. It is classified with GHS06 symbol and 'Danger' signal word, with hazard statements H300 (Fatal if swallowed) and H330 (Fatal if inhaled). Appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., N100 respirator), is essential. Always handle in a well-ventilated area or fume hood.
How is Eserine packed and shipped?
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Eserine is packed and shipped according to international regulations for hazardous materials, identified under UN 1544, Hazard Class 6.1, Packing Group I.
How can I request a quote or sample?
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To request a quote or sample of Eserine, please contact our sales team through the website or by phone. Provide your contact details and the required quantity.
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