Eserine hemisulfate salt
Eserine hemisulfate salt (CAS 64-47-1), with the molecular formula C15H21N3O2 · 0.5H2SO4 and a molecular weight of 324.39 g/mol, is a parasympathomimetic alkaloid derivative. It functions as a potent, reversible acetylcholinesterase inhibitor. This compound is primarily utilised in biochemical research for studying cholinergic neurotransmission and in the development of diagnostic tools for cholinesterase activity.
- IUPAC
- Physostigmine hemisulfate salt
- Synonyms
- Physostigmine hemisulfate salt

Acetylcholinesterase Inhibition Studies
Eserine hemisulfate salt serves as a crucial reagent for in vitro research focused on the mechanisms of acetylcholinesterase (AChE) activity and inhibition. It aids in understanding enzyme kinetics and the effects of various substances on the cholinergic system.
Neuroscience Research
This compound is applied in neuroscience to investigate the role of acetylcholine in synaptic transmission and neuronal function. Its ability to block the breakdown of acetylcholine makes it valuable for studying cholinergic pathways.
Diagnostic Reagent Development
It is used in the development and validation of assays and kits designed to detect or quantify cholinesterase activity, particularly in analytical and industrial enzyme applications.
| Molecular weight | 324.39 |
|---|---|
| Empirical formula | C15H21N3O2 · 0.5H2SO4 |
| Storage temperature | 2-8°C |

Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/28 |
| Safety statements (S) | 25-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Eserine hemisulfate salt used for?
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Eserine hemisulfate salt is primarily used in research for studying acetylcholinesterase inhibition and its effects on cholinergic neurotransmission, as well as in the development of diagnostic reagents.
What are the CAS number and formula for Eserine hemisulfate salt?
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The CAS number is 64-47-1 and the empirical formula is C15H21N3O2 · 0.5H2SO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Eserine hemisulfate salt typically as a research or technical grade chemical. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
How should Eserine hemisulfate salt be handled?
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Eserine hemisulfate salt is classified as acutely toxic if swallowed or inhaled (H300 + H330) and requires extreme caution during handling. Use with adequate ventilation, wear appropriate personal protective equipment (PPE) including respiratory protection (P260, P284), and avoid contact with skin and eyes (P264). In case of exposure, seek immediate medical attention (P301 + P310, P310).
How is Eserine hemisulfate salt packaged and shipped?
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Eserine hemisulfate salt is packaged according to regulatory requirements for hazardous materials and is exported globally by Tech Serve Solutions. It is assigned UN 2811, Hazard Class 6.1, Packing Group I.
How can I request a sample or quote for Eserine hemisulfate salt?
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To request a sample or a quote for Eserine hemisulfate salt, please contact our sales team through the website or by phone, providing your specific requirements.
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