Endothall
Endothall (CAS: 145-73-3), with the molecular formula C8H10O5 and a molecular weight of 186.16 g/mol, is a chemical compound primarily recognised for its role as a phosphatase inhibitor. It specifically targets Protein Phosphatase 2 (PP2), influencing serine/threonine kinase and phosphatase pathways. Its applications extend across cell biology and cell signalling research, making it a valuable reagent for scientific investigation.
- IUPAC
- 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
- Synonyms
- 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
Research Tool in Cell Biology
Endothall serves as a critical research tool for investigating cellular processes. Its ability to inhibit protein phosphatase 2 (PP2) allows scientists to study the effects of phosphatase activity on various cellular functions and signalling cascades.
Investigating Kinase/Phosphatase Pathways
This compound is instrumental in understanding the complex interplay between kinases and phosphatases. By selectively inhibiting PP2, researchers can elucidate the roles of these enzymes in pathways such as serine/threonine kinase biology.
Neuroscience Research
Endothall finds utility in neuroscience research, particularly in studies related to cell signalling. Its impact on neuronal pathways can be explored to understand its effects on nervous system functions.
| Molecular weight | 186.16 |
|---|---|
| Empirical formula | C8H10O5 |
Hazard statements
- H300Fatal if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 21-25-36/37/38 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Endothall used for?
+
Endothall is primarily used as a research tool in cell biology and neuroscience to investigate cell signalling and kinase/phosphatase pathways, particularly by inhibiting Protein Phosphatase 2 (PP2).
What is the CAS number and formula for Endothall?
+
The CAS number for Endothall is 145-73-3, and its empirical formula is C8H10O5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Endothall. The specific grade and purity (assay) are detailed on the product page. We do not represent this product as USP, BP, EP, or for human/veterinary use.
What are the primary safety hazards associated with Endothall?
+
Endothall is classified as acutely toxic if swallowed (H300) and harmful in contact with skin (H312). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is also very toxic to aquatic life (H400). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator.
How is Endothall packed, shipped, and exported?
+
Endothall is carefully packed to ensure stability and safety during transit. As a global supplier, Tech Serve Solutions adheres to all relevant international shipping regulations for hazardous materials (UN 2811, 6.1/PG 2) for export.
How can I request a sample or quote for Endothall?
+
To request a sample or a quotation for Endothall, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis