DMOG

CAS 89464-63-1C6H9NO5Cell Biology

DMOG (CAS: 89464-63-1), a small molecule with the formula C6H9NO5 and a molecular weight of 175.14 g/mol, is an inhibitor of aerobic glycolysis. Also known as Dimethyloxalylglycine, this compound plays a crucial role in cancer metabolism research. It is primarily utilised as a research tool to study the Warburg effect and related cellular processes, aiding investigations into gene regulation and cell signaling pathways. DMOG is supplied by TSS with an assay of ≥98% (HPLC).

IUPAC: Dimethyloxalylglycine,N-(Methoxyoxoacetyl)-glycine methyl ester
Synonyms: DimethyloxalylglycineN-(Methoxyoxoacetyl)-glycine methyl ester

Email us

DMOG (C6H9NO5) — chemical structure, CAS 89464-63-1; Life Science, fine chemical supplied by Tech Serve Solutions

Cancer MetabolismCancer ResearchCell Biology

01 /Applications

Cancer Metabolism Research

DMOG is extensively used to investigate the Warburg effect, a hallmark of cancer cell metabolism characterized by increased glycolysis even in the presence of oxygen. Researchers utilize DMOG to probe the mechanisms driving this phenomenon and its implications in tumour progression.

Hypoxia-Inducible Factor (HIF) Pathway Studies

As a HIF prolyl-hydroxylase inhibitor, DMOG is instrumental in studying cellular responses to hypoxia. By stabilizing HIF, it influences gene expression related to angiogenesis, cell survival, and metabolism, making it valuable for research in various physiological and pathological conditions.

Cell Biology and Gene Regulation

DMOG serves as a tool in cell biology to understand how metabolic shifts impact gene regulation and cell signaling. Its ability to modulate aerobic glycolysis provides insights into cellular energy production and its influence on cellular functions and differentiation.

02 /Properties

Molecular weight	175.14
Empirical formula	C6H9NO5
Assay	≥98% (HPLC)
Colour	white to off-white
Solubility	H2O: >30 mg/mL
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

89464-63-1

05 /Additional specifications

Shipped In	wet ice

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is DMOG primarily used for?

DMOG (CAS: 89464-63-1) is primarily used as a research chemical to study aerobic glycolysis (the Warburg effect) and its role in cancer metabolism, as well as for investigating hypoxia-inducible factor (HIF) pathways and their downstream effects on gene regulation and cell signaling.

What are the CAS number and formula for DMOG?

The CAS number for DMOG is 89464-63-1, and its empirical formula is C6H9NO5.

What grade and purity does Tech Serve Solutions supply for DMOG?

Tech Serve Solutions supplies DMOG with an assay of ≥98% determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.

What are the safety concerns when handling DMOG?

DMOG is classified with the GHS07 symbol and a 'Warning' signal word. It carries the hazard statement H302, indicating it is harmful if swallowed. Appropriate personal protective equipment should be used, and ingestion must be avoided during handling.

How is DMOG shipped and stored?

DMOG is shipped on wet ice and should be stored at −20°C to maintain its stability and integrity.

How can I request a quote or sample for DMOG?

To request a quote or sample for DMOG, please contact our sales team via the website or by phone, providing your contact details and the quantity required.