DNQX

CAS 2379-57-9C8H4N4O6Cell Biology

DNQX (CAS: 2379-57-9), with the molecular formula C8H4N4O6 and a molecular weight of 252.14 g/mol, is a potent antagonist of AMPA and kainate receptors. This non-competitive antagonist plays a crucial role in neuroscientific research by selectively blocking fast excitatory synaptic transmission mediated by glutamate. Its precise mechanism aids in studying neuronal excitability and receptor function.

IUPAC: 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione
Synonyms: 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione

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DNQX (C8H4N4O6) — chemical structure, CAS 2379-57-9; Life Science, fine chemical supplied by Tech Serve Solutions

AMPA/Kainate AntagonistsBioactive Small MoleculesCell BiologyDIG-DYExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters More...

01 /Applications

Neuroscience Research Tool

DNQX serves as a vital research tool for investigating the roles of AMPA and kainate receptors in synaptic transmission, neuronal plasticity, and various neurological processes. It is essential for dissecting excitatory neurotransmission pathways.

Investigating Excitotoxicity

As an antagonist of excitatory amino acid receptors, DNQX is used to study excitotoxicity, a process implicated in neuronal damage following stroke or neurodegenerative diseases. Its application helps researchers understand protective strategies.

Cellular Signaling Studies

DNQX aids in the study of cellular signaling pathways modulated by glutamate receptors, contributing to a deeper understanding of neuronal function and dysfunction in various physiological and pathological conditions.

02 /Properties

Molecular weight	252.14
Empirical formula	C8H4N4O6
Assay	≥98% (TLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2379-57-9

MDL number

MFCD00069257

PubChem substance

24277973

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DNQX used for?

DNQX is primarily used in neuroscience research as a selective antagonist for AMPA and kainate receptors, helping to study excitatory synaptic transmission, neuronal plasticity, and excitotoxicity.

What are the CAS number and molecular formula for DNQX?

The CAS number for DNQX is 2379-57-9, and its molecular formula is C8H4N4O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies DNQX with a purity of ≥98% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.

What safety precautions should be taken when handling DNQX?

When handling DNQX, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3, indicating a high hazard.

How is DNQX packed, shipped, and exported?

DNQX is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions. Specific packaging details can be provided upon request for order fulfillment.

How can I request a quote or sample for DNQX?

To request a quote or sample for DNQX, please contact our sales team through the website or by phone. Our representatives will assist you with your inquiry.