Diphenyl(o-tolyl)phosphine
Diphenyl(o-tolyl)phosphine (CAS: 5931-53-3) is a white to off-white crystalline solid with a molecular weight of 276.31 g/mol. As a key phosphine ligand, it serves as a valuable catalyst in various organic synthesis reactions, particularly in cross-coupling and cycloaddition processes. Its specific structural features enable diverse catalytic applications, contributing to efficient chemical transformations in research and development.
- IUPAC
- (2-Methylphenyl)diphenylphosphine
- Synonyms
- (2-Methylphenyl)diphenylphosphine
Catalysis in Organic Synthesis
Diphenyl(o-tolyl)phosphine functions as a catalyst in critical organic transformations. It facilitates three-component [3+2] cycloadditions, enabling the formation of complex cyclic structures from simpler precursors. Its utility extends to stereoselective olefination reactions, promoting the formation of alkenes with defined stereochemistry.
Cross-Coupling Reactions
This phosphine ligand is employed as a catalyst in Suzuki coupling reactions, a cornerstone of modern organic synthesis for C-C bond formation. It also participates in other coupling reactions, making it a versatile tool for constructing intricate molecular architectures.
Hydroxycarbonylation Catalyst
Diphenyl(o-tolyl)phosphine acts as a catalyst in hydroxycarbonylation reactions. This process introduces a hydroxyl group and a carbonyl group into organic molecules, offering a pathway to valuable carboxylic acid derivatives.
| Molecular weight | 276.31 |
|---|---|
| Linear formula | (C6H5)2PC6H4CH3 |
| Assay | 98% |
| Application | Catalyst for:• Three component [3+2] cycloadditions1• Suzuki coupling2• Stereoselective olefination3• Coupling reactions4• Hydroxycarbonylation5 |
| Melting point | 70-73 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diphenyl(o-tolyl)phosphine used for?
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Diphenyl(o-tolyl)phosphine is primarily used as a catalyst and ligand in various organic synthesis reactions, including three-component [3+2] cycloadditions, Suzuki coupling, stereoselective olefination, general coupling reactions, and hydroxycarbonylation.
What is the CAS number and chemical formula for Diphenyl(o-tolyl)phosphine?
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The CAS number for Diphenyl(o-tolyl)phosphine is 5931-53-3. Its linear formula is (C₆H₅)₂PC₆H₄CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diphenyl(o-tolyl)phosphine with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should Diphenyl(o-tolyl)phosphine be handled safely?
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Handle Diphenyl(o-tolyl)phosphine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Diphenyl(o-tolyl)phosphine a controlled substance?
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The provided data does not indicate that Diphenyl(o-tolyl)phosphine is a controlled substance.
How is Diphenyl(o-tolyl)phosphine packaged and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details for Diphenyl(o-tolyl)phosphine are available upon request, adhering to international shipping regulations.
How can I request a quote or sample for Diphenyl(o-tolyl)phosphine?
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To request a quote or sample for Diphenyl(o-tolyl)phosphine, please contact our sales team through the website or by phone.
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