Ingenol-3-angelate
Ingenol-3-angelate (CAS: 75567-37-2), with the molecular formula C25H34O6 and a molecular weight of 430.53 g/mol, is a naturally occurring compound derived from Euphorbia species. It presents as an amorphous, clear substance. This compound is recognised for its role in cell signaling pathways, particularly concerning Protein Kinase C (PKC) activation, making it valuable in biochemical research and studies of cell biology and neuroscience.
- IUPAC
- I3A,PEP005
Cell Signaling Research
Ingenol-3-angelate serves as a valuable tool for investigating the intricate pathways of cell signaling. It is widely used to study the activation and function of Protein Kinase C (PKC) and related serine/threonine kinases.
Biochemical Investigations
As a bioactive small molecule, Ingenol-3-angelate is employed in various biochemical assays to understand cellular responses and mechanisms. Its specific interactions within cellular pathways are a focus of research.
Neuroscience Studies
The compound's influence on cell signaling pathways makes it relevant for research in neuroscience, aiding the exploration of cellular communication and function within the nervous system.
Phytochemical Analysis
Ingenol-3-angelate is a key phytochemical derived from Euphorbia species. Its isolation and study contribute to the understanding of plant-derived compounds and their biological activities.
| Molecular weight | 430.53 |
|---|---|
| Empirical formula | C25H34O6 |
| Assay | ≥98% (HPLC) |
| Form | amorphous |
| Colour | clear |
| Solubility | DMSO: >1 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ingenol-3-angelate used for?
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Ingenol-3-angelate is primarily used in biochemical and cell biology research for studying cell signaling pathways, particularly the activation of Protein Kinase C (PKC) and serine/threonine kinases. It is also relevant in neuroscience and phytochemical investigations.
What are the CAS number and formula for Ingenol-3-angelate?
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The CAS number for Ingenol-3-angelate is 75567-37-2, and its molecular formula is C25H34O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ingenol-3-angelate with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for Ingenol-3-angelate?
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When handling Ingenol-3-angelate, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The product has a WGK Germany rating of 3.
How is Ingenol-3-angelate stored and shipped?
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Ingenol-3-angelate should be stored at -20°C. It is soluble in DMSO at concentrations greater than 1 mg/mL. TSS can export this chemical globally.
How can I request a sample or quote for Ingenol-3-angelate?
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Please contact the TSS sales team via our website or direct inquiry to request a sample or obtain a quotation for Ingenol-3-angelate.
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