Diphenyl(p-tolyl)phosphine
Diphenyl(p-tolyl)phosphine (CAS: 1031-93-2), with the linear formula (C<sub>6</sub>H<sub>5</sub>)<sub>2</sub>PC<sub>6</sub>H<sub>4</sub>CH<sub>3</sub> and a molecular weight of 276.31 g/mol, is a phosphine compound used as a reactant in chemical synthesis. It is particularly valuable in catalysis and as a phosphine ligand, participating in reactions such as three-component cyclizations and the formation of palladium pincer complexes. This compound serves as a key intermediate for specialised inorganic and organic synthesis.
- IUPAC
- (4-Methylphenyl)diphenyl phosphine
- Synonyms
- (4-Methylphenyl)diphenyl phosphine

Catalyst Ligand Synthesis
Utilised in the formation of palladium pincer complexes, enabling probing of coordination abilities in catalytic systems. It also acts as a reactant for synthesising trinuclear ruthenium carbonyl triarylphosphine cluster complexes.
Organic Synthesis Intermediate
Serves as a reactant in three-component cyclization reactions. It is also employed in the chelation-assisted hydroacylation of olefins with primary alcohols, facilitating complex molecule assembly.
Materials Science Precursor
Acts as a precursor for the synthesis of InP nanofibers and other metal phosphide nanostructures, important for advanced material applications.
Medicinal Chemistry Research
A reactant in the synthesis of leishmanicidal leads that target mitochondria by inhibiting the respiratory complex, contributing to drug discovery efforts.
| Molecular weight | 276.31 |
|---|---|
| Linear formula | (C6H5)2PC6H4CH3 |
| Assay | 96% |
| Application | Reactant for:• Three-component cyclization1• Probing coordination ability via a palladium pincer complex2• Chelation-assisted hydroacylation of olefins with primary alcohols3Reactant for synthesis of:• Trinuclear ruthenium carbonyl triarylphosphine cluster complexes4• Leishmanicidal leads targeting mitochondria through inhibition of the respiratory complex5• InP nanofibers / metal phosphide nanostructures6• Peroxyl radical cations via pulse radiolysis one-electron oxidations7 |
| Melting point | 66-68 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diphenyl(p-tolyl)phosphine used for?
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Diphenyl(p-tolyl)phosphine is used as a reactant in various chemical syntheses, including three-component cyclizations, probing coordination ability via palladium pincer complexes, and chelation-assisted hydroacylation of olefins. It is also a precursor for trinuclear ruthenium carbonyl triarylphosphine cluster complexes, leishmanicidal leads, InP nanofibers, and metal phosphide nanostructures.
What is the CAS number and chemical formula for Diphenyl(p-tolyl)phosphine?
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The CAS number is 1031-93-2 and the linear chemical formula is (C<sub>6</sub>H<sub>5</sub>)<sub>2</sub>PC<sub>6</sub>H<sub>4</sub>CH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diphenyl(p-tolyl)phosphine with an assay of 96%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Diphenyl(p-tolyl)phosphine be handled safely?
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Diphenyl(p-tolyl)phosphine is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is this chemical available for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and Diphenyl(p-tolyl)phosphine can be exported internationally. Please contact us for specific shipping details and regulations.
How can I request a quote or sample?
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To request a quote or a sample of Diphenyl(p-tolyl)phosphine, please visit our website or contact our sales team directly. Provide the product name and CAS number (1031-93-2) for prompt service.
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