Dihydrofolic acid
Dihydrofolic acid (CAS: 4033-27-6; C19H21N7O6) is a crucial intermediate in folate metabolism. It is a key cofactor in biological systems, playing a vital role in one-carbon transfer reactions essential for nucleotide and amino acid synthesis. This compound is primarily utilised in biochemical research and as a reference standard for studies involving folate pathways and related enzyme activities.
- IUPAC
- 7,8-Dihydropteroyl-L-glutamic acid,Dihydropteroyl-L-glutamic acid,FAH2
- Synonyms
- 7,8-Dihydropteroyl-L-glutamic acidDihydropteroyl-L-glutamic acidFAH2
Biochemical Research
Dihydrofolic acid serves as a valuable tool in biochemical research, particularly for investigating enzyme kinetics and metabolic pathways. It is used to study enzymes like dihydrofolate reductase and understand the intricate processes of cellular metabolism.
Cofactor Studies
As a derivative of folic acid, it functions as a cofactor in various biological reactions. Researchers utilise it to explore the mechanisms of one-carbon transfer essential for DNA synthesis and amino acid interconversion.
Enzyme Inhibition Studies
Dihydrofolic acid can be employed in studies related to enzyme inhibition. Its structural similarity to natural substrates allows for investigations into the mechanisms by which certain compounds might interfere with folate metabolism.
| Molecular weight | 443.41 |
|---|---|
| Empirical formula | C19H21N7O6 |
| Assay | ≥90% |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DHFRP1(573971)mouse ... Dhfr(13361) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dihydrofolic acid used for?
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Dihydrofolic acid is primarily used in biochemical research to study folate metabolism, enzyme kinetics, and as a cofactor in one-carbon transfer reactions. It is also utilised in enzyme inhibition studies.
What are the CAS number and formula for Dihydrofolic acid?
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The CAS number for Dihydrofolic acid is 4033-27-6, and its empirical formula is C19H21N7O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dihydrofolic acid with an assay of ≥90%. We do not represent this product as USP, BP, or EP grade.
How should Dihydrofolic acid be handled and stored?
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Handle Dihydrofolic acid with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. It should be stored at -20°C. Refer to the safety data sheet for detailed handling instructions.
Is Dihydrofolic acid a controlled substance?
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Based on the provided data, Dihydrofolic acid is not listed as a controlled substance.
How can I request a sample or quote for Dihydrofolic acid?
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To request a sample or a quote for Dihydrofolic acid, please contact our sales team through the website or by phone.
How is Dihydrofolic acid packed and exported?
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Dihydrofolic acid is packed according to industry standards for chemical stability and safety during transport. TSS is a global supplier and exporter.
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