2-Methoxy-2,4-diphenyl-3(2H)-furanone
2-Methoxy-2,4-diphenyl-3(2H)-furanone (CAS: 50632-57-0) is a chemical compound with the molecular formula C17H14O3 and a molecular weight of 266.29. It is specifically utilised as a fluorescence reagent for the derivatisation of primary and secondary amines. This process enables sensitive detection and analysis of amines in various scientific applications, including chromatography and electrophoresis.
- IUPAC
- 2,4-Diphenyl-2-methoxy-3(2H)-furanone,MDPF
- Synonyms
- 2,4-Diphenyl-2-methoxy-3(2H)-furanoneMDPF
Fluorescence Derivatisation
2-Methoxy-2,4-diphenyl-3(2H)-furanone (MDPF) is employed to react with primary and secondary amines, converting them into fluorescent derivatives. This enhancement is crucial for improving detection limits in analytical procedures.
Chromatographic Analysis
The fluorescent derivatives formed with MDPF can be effectively detected and quantified using various chromatographic techniques, such as HPLC. This application is vital for the analysis of complex mixtures containing amines.
Electrophoretic Separations
MDPF derivatisation is also valuable in electrophoretic methods, allowing for the sensitive visualisation and analysis of amine-containing molecules separated by charge and size.
Zymography
The fluorescence properties imparted by MDPF derivatisation can aid in zymography techniques, facilitating the detection of specific enzyme activities within complex biological samples.
| Molecular weight | 266.29 |
|---|---|
| Empirical formula | C17H14O3 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Application | 2-Methoxy-2,4-diphenyl-3(2H)-furanone (MDPF) is used as a fluorescence reagent to derivatize primary and secondary amines on molecules such as proteins. MDPF derivatized molecules can be detected during analytical and separation procedures including chromatography, electrophoresis and zymography. |
| Suitability | suitable for fluorescence |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 384 nm; λem 472 nm in acetonitrile (after derivatization with hexylamine) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-2,4-diphenyl-3(2H)-furanone used for?
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2-Methoxy-2,4-diphenyl-3(2H)-furanone is used as a fluorescence reagent to derivatise primary and secondary amines, enabling their detection in analytical and separation procedures like chromatography, electrophoresis, and zymography.
What are the CAS number and formula for 2-Methoxy-2,4-diphenyl-3(2H)-furanone?
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The CAS number for 2-Methoxy-2,4-diphenyl-3(2H)-furanone is 50632-57-0 and its empirical formula is C17H14O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxy-2,4-diphenyl-3(2H)-furanone with a purity of ≥98.0% (HPLC). This product is supplied for research and technical purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Methoxy-2,4-diphenyl-3(2H)-furanone be handled?
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When handling, it is recommended to wear a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling and safety information.
Is 2-Methoxy-2,4-diphenyl-3(2H)-furanone shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Methoxy-2,4-diphenyl-3(2H)-furanone.
How can I request a sample or quote for 2-Methoxy-2,4-diphenyl-3(2H)-furanone?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (50632-57-0).
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