2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride
2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride (CAS: 126565-42-2) is a specialised organic compound with the molecular formula C15H12ClNO4S and a molecular weight of 337.78 g/mol. Its key feature is its utility as a derivatisation reagent, particularly for fluorescence detection in analytical applications like HPLC. It is supplied with a purity of ≥97.0% (CHN) and is suitable for fluorescence derivatisation.
- IUPAC
- M-Phisyl chloride

HPLC Derivatisation Reagent
This compound serves as an effective derivatisation agent for High-Performance Liquid Chromatography (HPLC). It facilitates the detection of analytes by introducing a fluorescent tag, enhancing sensitivity and selectivity in chromatographic analysis.
Fluorescence Detection
Utilised for creating fluorescent derivatives, this reagent is particularly valuable in analytical methods requiring sensitive detection. Its fluorescence properties (λex 330 nm; λem 427 nm in chloroform after derivatization) enable quantification of trace analytes.
Analytical Chemistry
As a specialised analytical reagent, it finds application in various quantitative analyses where precise derivatisation is necessary. Its reactivity as a sulfonyl chloride allows for coupling with amines and other nucleophiles.
| Molecular weight | 337.78 |
|---|---|
| Empirical formula | C15H12ClNO4S |
| Assay | ≥97.0% (CHN) |
| Suitability | suitable for fluorescence |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 330 nm; λem 427 nm in chloroform (after derivatization with hexylamine) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride used for?
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This compound is primarily used as a derivatisation reagent, particularly for enhancing fluorescence detection in analytical techniques such as HPLC. It is suitable for creating fluorescent derivatives for sensitive quantification.
What is the CAS number and formula for 2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride?
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The CAS number is 126565-42-2. The empirical formula is C15H12ClNO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97.0% (CHN). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should this chemical be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves and respirators, must be worn. Handle in a well-ventilated area and follow all safety precautions for corrosive substances.
How is 2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride packed and shipped?
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The product is shipped as UN 3261, Class 8, Packing Group III, indicating it is a corrosive solid, acidic, organic, n.o.s. Packing and shipping adhere to international regulations for hazardous materials.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing the product name and CAS number (126565-42-2).
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